The impact of methods for estimating bone health and the global burden of bone disease
The impact of methods for estimating bone health and the global burden of bone disease
Osteoporosis constitutes a major public health problem through its association with age related fractures. Fracture rates are generally higher in caucasian women than in other populations. Important determinants include estrogen deficiency in women, low body mass index, cigarette smoking, alcohol consumption, poor dietary calcium intake, physical inactivity, certain drugs and illnesses. Thus, modification of physical activity and dietary calcium/vitamin D nutrition should complement high risk approaches. In addition, the recently developed WHO algorithm for evaluation of 10-year absolute risk of fracture provides a means whereby various therapies can be targeted cost-effectively to those at risk. Risk factors, together with bone mineral density (BMD) and biochemical indices of bone turnover, can be utilised to derive absolute risks of fracture and cost-utility thresholds at which treatment is justified. These data will provide the basis for translation into coherent public health strategies aiming to prevent osteoporosis both in individuals and in the general population
osteoporosis, fracture risk, prevention, bone density, risk factors, algorithm, absolute risk of fracture, public health
S38-S45
Cole, Zoë A.
6802e58a-59b3-4518-bb7d-6f721732cd61
Dennison, Elaine M.
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
2009
Cole, Zoë A.
6802e58a-59b3-4518-bb7d-6f721732cd61
Dennison, Elaine M.
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Cole, Zoë A., Dennison, Elaine M. and Cooper, Cyrus
(2009)
The impact of methods for estimating bone health and the global burden of bone disease.
Salud Pública de México, 51 (Supplement 1), .
Abstract
Osteoporosis constitutes a major public health problem through its association with age related fractures. Fracture rates are generally higher in caucasian women than in other populations. Important determinants include estrogen deficiency in women, low body mass index, cigarette smoking, alcohol consumption, poor dietary calcium intake, physical inactivity, certain drugs and illnesses. Thus, modification of physical activity and dietary calcium/vitamin D nutrition should complement high risk approaches. In addition, the recently developed WHO algorithm for evaluation of 10-year absolute risk of fracture provides a means whereby various therapies can be targeted cost-effectively to those at risk. Risk factors, together with bone mineral density (BMD) and biochemical indices of bone turnover, can be utilised to derive absolute risks of fracture and cost-utility thresholds at which treatment is justified. These data will provide the basis for translation into coherent public health strategies aiming to prevent osteoporosis both in individuals and in the general population
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Published date: 2009
Keywords:
osteoporosis, fracture risk, prevention, bone density, risk factors, algorithm, absolute risk of fracture, public health
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Local EPrints ID: 68875
URI: http://eprints.soton.ac.uk/id/eprint/68875
ISSN: 0036-3634
PURE UUID: 61ee466e-c46d-4e5b-a4b5-33526aa4711f
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Date deposited: 07 Oct 2009
Last modified: 18 Mar 2024 02:44
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Author:
Zoë A. Cole
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