The University of Southampton
University of Southampton Institutional Repository

Cardiovascular health of Finnish war evacuees 60 years later

Cardiovascular health of Finnish war evacuees 60 years later
Cardiovascular health of Finnish war evacuees 60 years later
Background: early life experiences might have long-term effects on health.
Aim: to assess prevalence of cardiovascular disease and diabetes in later life among individuals exposed to traumatic separation in early childhood due to World War II.
Methods: of the participants of the Helsinki Birth Cohort 1934-44 Study (n=2003), 320 had been evacuated abroad to temporary foster care in childhood. The remaining participants served as controls. The mean age at evacuation was 4.8 (SD=2.4) years and the mean duration of the evacuation was 1.7 (SD=1.0) years.
Results: cardiovascular morbidity was higher among the former war evacuees (14.7% versus 7.9%; odds ratio (OR)=2.0, 95% confidence interval (95% CI) 1.4-2.9; P<0.001). A similar difference in prevalence of type 2 diabetes was observed (19.7% versus 14.8%; OR=1.4, 95% CI 1.1-1.9, P=0.025). The former war evacuees were also more likely to be hypertensive (P<0.05). The effects on morbidity were not explained by age at testing or socio-economic circumstances in childhood or adulthood.
Conclusion: early life traumatic events may extend lifelong effects on health. This study is among the first to show that early life trauma predicts higher prevalence of cardiovascular disease and type 2 diabetes in late adulthood, in a longitudinal clinical study setting
cardiovascular disease, diabetes, life stress, programming
0785-3890
66-72
Alastalo, Hanna
3a5e2504-3d51-45db-9824-31588131da94
Raikkonen, Katri
7f44cbef-84f3-4d77-9ccc-f026ce537dd8
Pesonen, Anu-Katriina
8cc53fef-f713-425e-bd01-8f1c53842351
Osmond, Clive
2677bf85-494f-4a78-adf8-580e1b8acb81
Barker, David J.P.
5c773838-b094-4ac1-999b-b5869717f243
Kajantie, Eero
d68d55b6-6df1-4195-a914-44c738a6db93
Heinonen, Kati
46bb57d0-1c33-4cdd-badf-d38a5fc61200
Forsen, Tom J.
55342e20-c4a5-40e5-ad81-2a64c1e0f333
Eriksson, Johan G.
e95e6451-67bb-4338-803e-7af310a920ac
Alastalo, Hanna
3a5e2504-3d51-45db-9824-31588131da94
Raikkonen, Katri
7f44cbef-84f3-4d77-9ccc-f026ce537dd8
Pesonen, Anu-Katriina
8cc53fef-f713-425e-bd01-8f1c53842351
Osmond, Clive
2677bf85-494f-4a78-adf8-580e1b8acb81
Barker, David J.P.
5c773838-b094-4ac1-999b-b5869717f243
Kajantie, Eero
d68d55b6-6df1-4195-a914-44c738a6db93
Heinonen, Kati
46bb57d0-1c33-4cdd-badf-d38a5fc61200
Forsen, Tom J.
55342e20-c4a5-40e5-ad81-2a64c1e0f333
Eriksson, Johan G.
e95e6451-67bb-4338-803e-7af310a920ac

Alastalo, Hanna, Raikkonen, Katri, Pesonen, Anu-Katriina, Osmond, Clive, Barker, David J.P., Kajantie, Eero, Heinonen, Kati, Forsen, Tom J. and Eriksson, Johan G. (2009) Cardiovascular health of Finnish war evacuees 60 years later. Annals of Medicine, 41 (1), 66-72. (doi:10.1080/07853890802301983).

Record type: Article

Abstract

Background: early life experiences might have long-term effects on health.
Aim: to assess prevalence of cardiovascular disease and diabetes in later life among individuals exposed to traumatic separation in early childhood due to World War II.
Methods: of the participants of the Helsinki Birth Cohort 1934-44 Study (n=2003), 320 had been evacuated abroad to temporary foster care in childhood. The remaining participants served as controls. The mean age at evacuation was 4.8 (SD=2.4) years and the mean duration of the evacuation was 1.7 (SD=1.0) years.
Results: cardiovascular morbidity was higher among the former war evacuees (14.7% versus 7.9%; odds ratio (OR)=2.0, 95% confidence interval (95% CI) 1.4-2.9; P<0.001). A similar difference in prevalence of type 2 diabetes was observed (19.7% versus 14.8%; OR=1.4, 95% CI 1.1-1.9, P=0.025). The former war evacuees were also more likely to be hypertensive (P<0.05). The effects on morbidity were not explained by age at testing or socio-economic circumstances in childhood or adulthood.
Conclusion: early life traumatic events may extend lifelong effects on health. This study is among the first to show that early life trauma predicts higher prevalence of cardiovascular disease and type 2 diabetes in late adulthood, in a longitudinal clinical study setting

Full text not available from this repository.

More information

Published date: 2009
Keywords: cardiovascular disease, diabetes, life stress, programming

Identifiers

Local EPrints ID: 68982
URI: https://eprints.soton.ac.uk/id/eprint/68982
ISSN: 0785-3890
PURE UUID: 59276e98-f3f6-4acd-8037-8e222f99def0
ORCID for Clive Osmond: ORCID iD orcid.org/0000-0002-9054-4655

Catalogue record

Date deposited: 13 Oct 2009
Last modified: 12 Nov 2019 01:59

Export record

Altmetrics

Contributors

Author: Hanna Alastalo
Author: Katri Raikkonen
Author: Anu-Katriina Pesonen
Author: Clive Osmond ORCID iD
Author: David J.P. Barker
Author: Eero Kajantie
Author: Kati Heinonen
Author: Tom J. Forsen
Author: Johan G. Eriksson

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×