Inflammation in aging part 2: implications for health of older people and recommendations for nursing practice
Inflammation in aging part 2: implications for health of older people and recommendations for nursing practice
Aging is accompanied by declining function and remodeling of body systems. In particular, changes to the immune and endocrine systems have far-reaching effects that cause an increase in cytokine release and decrease in anti-inflammatory feedback systems. The chronic inflammation that ensues has been named "inflammaging." Inflammaging is associated with many detrimental effects that combine to increase morbidity and mortality. The sickness behavior that arises from inflammatory processes and the side effects of chronic diseases lead to a constellation of symptoms that decrease quality of life and affect the well-being of the individual. Part 2 of this two-part article provides an overview of the health effects of inflammaging, addressing the extent to which it contributes to the syndromes of frailty and disability with aging
253-260
Hunt, Katherine J.
74e3bd43-e130-489b-9565-74ce98a201f9
Walsh, Bronagh M.
5818243e-048d-4b4b-88c5-231b0e419427
Voegeli, David
9379133a-ed12-45a0-9c52-ed5a14c96dff
Roberts, Helen C.
eb72590b-27b2-478f-b1b9-89d036b270fa
Hunt, Katherine J.
74e3bd43-e130-489b-9565-74ce98a201f9
Walsh, Bronagh M.
5818243e-048d-4b4b-88c5-231b0e419427
Voegeli, David
9379133a-ed12-45a0-9c52-ed5a14c96dff
Roberts, Helen C.
eb72590b-27b2-478f-b1b9-89d036b270fa
Hunt, Katherine J., Walsh, Bronagh M., Voegeli, David and Roberts, Helen C.
(2009)
Inflammation in aging part 2: implications for health of older people and recommendations for nursing practice.
Biological Research for Nursing, 11, .
(10.117/1099800409352377).
(Submitted)
Abstract
Aging is accompanied by declining function and remodeling of body systems. In particular, changes to the immune and endocrine systems have far-reaching effects that cause an increase in cytokine release and decrease in anti-inflammatory feedback systems. The chronic inflammation that ensues has been named "inflammaging." Inflammaging is associated with many detrimental effects that combine to increase morbidity and mortality. The sickness behavior that arises from inflammatory processes and the side effects of chronic diseases lead to a constellation of symptoms that decrease quality of life and affect the well-being of the individual. Part 2 of this two-part article provides an overview of the health effects of inflammaging, addressing the extent to which it contributes to the syndromes of frailty and disability with aging
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Submitted date: 23 November 2009
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Local EPrints ID: 69904
URI: http://eprints.soton.ac.uk/id/eprint/69904
DOI: 10.117/1099800409352377
ISSN: 1099-8004
PURE UUID: e9ea3ba7-7a49-4838-a34a-929df032bf2c
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Date deposited: 10 Dec 2009
Last modified: 14 Mar 2024 02:42
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Author:
Katherine J. Hunt
Author:
David Voegeli
Author:
Helen C. Roberts
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