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Generalised anxiety disorder is associated with metabolic syndrome in the Vietnam experience study

Generalised anxiety disorder is associated with metabolic syndrome in the Vietnam experience study
Generalised anxiety disorder is associated with metabolic syndrome in the Vietnam experience study
Background
Few studies have explored the relationship between major mental health disorders and metabolic syndrome (MetS), although both have been linked to cardiovascular disease. The present study examined the cross-sectional associations of major depressive disorder (MDD) and generalized anxiety disorder (GAD) with MetS in a large study of male US veterans. Methods
The analyses were cross-sectional. Participants (n = 4256) were drawn from the Vietnam Experience Study. From military service files, telephone interviews, and a medical examination, occupational, socio-demographic, and health data were collected. One-year prevalence of MDD and GAD was determined with DSM-III criteria. Metabolic syndrome was ascertained from data on: body mass index, fasting blood glucose or a diagnosis of diabetes, blood pressure, high-density lipoprotein cholesterol, and triglyceride levels. Results
In models that adjusted for age (p = .01) and additionally for place of service, ethnicity, marital status, smoking, alcohol consumption, IQ at enlistment, household income in midlife, and education grade achieved (p = .02), GAD was positively associated with MetS. Major depressive disorder was not related to MetS. Conclusions
Depression has very much been the focal condition for studies on mental health and physical health outcomes. The current data suggest that future research should perhaps pay equal attention to GAD.
0006-3223
91-93
Carroll, D.
5768ff5c-aa0b-49ff-ba36-3cf02eded0b8
Phillips, A.C.
873973d2-7aa6-461a-bba8-95ddc0c317d8
Thomas, G.N.
3635b162-ce4e-4257-86a1-992b7a570505
Gale, C.R.
5bb2abb3-7b53-42d6-8aa7-817e193140c8
Deary, I.J.
e3403cfe-eb5b-4941-903d-87ef0db89c60
Batty, G.D.
bf322937-2cfb-4174-b5cb-dc016f0d0b8a
Carroll, D.
5768ff5c-aa0b-49ff-ba36-3cf02eded0b8
Phillips, A.C.
873973d2-7aa6-461a-bba8-95ddc0c317d8
Thomas, G.N.
3635b162-ce4e-4257-86a1-992b7a570505
Gale, C.R.
5bb2abb3-7b53-42d6-8aa7-817e193140c8
Deary, I.J.
e3403cfe-eb5b-4941-903d-87ef0db89c60
Batty, G.D.
bf322937-2cfb-4174-b5cb-dc016f0d0b8a

Carroll, D., Phillips, A.C., Thomas, G.N., Gale, C.R., Deary, I.J. and Batty, G.D. (2009) Generalised anxiety disorder is associated with metabolic syndrome in the Vietnam experience study. Biological Psychiatry, 66 (1), 91-93. (doi:10.1016/j.biopsych.2009.02.020).

Record type: Article

Abstract

Background
Few studies have explored the relationship between major mental health disorders and metabolic syndrome (MetS), although both have been linked to cardiovascular disease. The present study examined the cross-sectional associations of major depressive disorder (MDD) and generalized anxiety disorder (GAD) with MetS in a large study of male US veterans. Methods
The analyses were cross-sectional. Participants (n = 4256) were drawn from the Vietnam Experience Study. From military service files, telephone interviews, and a medical examination, occupational, socio-demographic, and health data were collected. One-year prevalence of MDD and GAD was determined with DSM-III criteria. Metabolic syndrome was ascertained from data on: body mass index, fasting blood glucose or a diagnosis of diabetes, blood pressure, high-density lipoprotein cholesterol, and triglyceride levels. Results
In models that adjusted for age (p = .01) and additionally for place of service, ethnicity, marital status, smoking, alcohol consumption, IQ at enlistment, household income in midlife, and education grade achieved (p = .02), GAD was positively associated with MetS. Major depressive disorder was not related to MetS. Conclusions
Depression has very much been the focal condition for studies on mental health and physical health outcomes. The current data suggest that future research should perhaps pay equal attention to GAD.

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More information

Submitted date: 24 November 2008
Published date: 1 July 2009

Identifiers

Local EPrints ID: 69959
URI: https://eprints.soton.ac.uk/id/eprint/69959
ISSN: 0006-3223
PURE UUID: 6f8b53c8-4308-4ffa-b683-d083594c1655
ORCID for C.R. Gale: ORCID iD orcid.org/0000-0002-3361-8638

Catalogue record

Date deposited: 05 Jan 2010
Last modified: 06 Feb 2019 01:37

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