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Diarrhoea in childhood and cause-specific mortality in older age: analyses of 5642 deaths in 33261 individuals from the Hertfordshire studies

Diarrhoea in childhood and cause-specific mortality in older age: analyses of 5642 deaths in 33261 individuals from the Hertfordshire studies
Diarrhoea in childhood and cause-specific mortality in older age: analyses of 5642 deaths in 33261 individuals from the Hertfordshire studies
The objective of these analyses were to examine if episodes of diarrhoea in childhood are related to adult coronary heart disease (CHD) mortality. Data were pooled from two prospective UK cohort studies (participants born 1923-1939). Reported diarrhoea in infancy (3.1%) and between 1 and 5 years (1.1%) was rare. No relationship between diarrhoea in infancy and CHD mortality or mortality from all-causes and cardiovascular disease was observed. Although diarrhoea between 1 and 5 years was also not related to CHD risk, slightly lower rates of total and cardiovascular disease mortality were apparent in this group relative to the diarrhoea-free. In the largest study to date to examine the relation, there was no evidence that diarrhoea in early life had an influence on later CHD mortality. EurJ Cardiovasc PrevRehabil 15:494-496 (c) 2008 The European Society of Cardiology
disease, infancy, risk, life, coronary-heart-disease, cohort, adult, cardiovascular disease, coronary heart disease, early-life, children, hertfordshire, dehydration, cardiovascular-disease, heart, england, blood-pressure, childhood, mortality, cardiology, diarrhoea, cohort studies
1741-8267
494-496
Batty, G. David
605ce199-493d-4238-b9c8-a2c076672e83
Smith, George Davey
f5bc8327-f2cb-49a0-8eae-4a6ba63207a2
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Gale, Catharine R.
5bb2abb3-7b53-42d6-8aa7-817e193140c8
Batty, G. David
605ce199-493d-4238-b9c8-a2c076672e83
Smith, George Davey
f5bc8327-f2cb-49a0-8eae-4a6ba63207a2
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Gale, Catharine R.
5bb2abb3-7b53-42d6-8aa7-817e193140c8

Batty, G. David, Smith, George Davey, Cooper, Cyrus and Gale, Catharine R. (2008) Diarrhoea in childhood and cause-specific mortality in older age: analyses of 5642 deaths in 33261 individuals from the Hertfordshire studies. European Journal Cardiovascular Prevention & Rehabilitation, 15 (4), 494-496. (doi:10.1097/01.HJR.0b013e3282ffaffa).

Record type: Article

Abstract

The objective of these analyses were to examine if episodes of diarrhoea in childhood are related to adult coronary heart disease (CHD) mortality. Data were pooled from two prospective UK cohort studies (participants born 1923-1939). Reported diarrhoea in infancy (3.1%) and between 1 and 5 years (1.1%) was rare. No relationship between diarrhoea in infancy and CHD mortality or mortality from all-causes and cardiovascular disease was observed. Although diarrhoea between 1 and 5 years was also not related to CHD risk, slightly lower rates of total and cardiovascular disease mortality were apparent in this group relative to the diarrhoea-free. In the largest study to date to examine the relation, there was no evidence that diarrhoea in early life had an influence on later CHD mortality. EurJ Cardiovasc PrevRehabil 15:494-496 (c) 2008 The European Society of Cardiology

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More information

Published date: August 2008
Keywords: disease, infancy, risk, life, coronary-heart-disease, cohort, adult, cardiovascular disease, coronary heart disease, early-life, children, hertfordshire, dehydration, cardiovascular-disease, heart, england, blood-pressure, childhood, mortality, cardiology, diarrhoea, cohort studies

Identifiers

Local EPrints ID: 70284
URI: https://eprints.soton.ac.uk/id/eprint/70284
ISSN: 1741-8267
PURE UUID: 0411a3da-e11f-4039-a4a4-50e266d991f6
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for Catharine R. Gale: ORCID iD orcid.org/0000-0002-3361-8638

Catalogue record

Date deposited: 28 Jan 2010
Last modified: 06 Feb 2019 01:37

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