The University of Southampton
University of Southampton Institutional Repository

Bend those knees!

Bend those knees!
Bend those knees!
Our evolutionary success as vertebrates has been in large part due to the development and positioning of the synovial joint, sitting as it does between our long bones, to enable us to move smoothly. Synovial fluid, the visco-elastic material filling the joint cavity, serves not only as a lubricant and a shock absorber but is also an important source of nutrients for the joint cartilage (Fam et al. 2007). One of the major components of synovial fluid and central to its rheological and other properties is the glycosaminoglycan, hyaluronic acid (HA). HA, composed of repeated disaccharide units of N-acetylglucosamine and d-glucuronic acid, has an average molecular mass of 1 × 106 Da. Its concentration in human synovial fluid is between 2 and 4 mg ml?1.
0022-3751
p.1462
Clough, Geraldine
9f19639e-a929-4976-ac35-259f9011c494
Clough, Geraldine
9f19639e-a929-4976-ac35-259f9011c494

Clough, Geraldine (2008) Bend those knees! The Journal of Physiology, 586 (6), p.1462. (doi:10.1113/jphysiol.2008.151464).

Record type: Article

Abstract

Our evolutionary success as vertebrates has been in large part due to the development and positioning of the synovial joint, sitting as it does between our long bones, to enable us to move smoothly. Synovial fluid, the visco-elastic material filling the joint cavity, serves not only as a lubricant and a shock absorber but is also an important source of nutrients for the joint cartilage (Fam et al. 2007). One of the major components of synovial fluid and central to its rheological and other properties is the glycosaminoglycan, hyaluronic acid (HA). HA, composed of repeated disaccharide units of N-acetylglucosamine and d-glucuronic acid, has an average molecular mass of 1 × 106 Da. Its concentration in human synovial fluid is between 2 and 4 mg ml?1.

Full text not available from this repository.

More information

Published date: 1 March 2008
Organisations: Dev Origins of Health & Disease

Identifiers

Local EPrints ID: 70335
URI: https://eprints.soton.ac.uk/id/eprint/70335
ISSN: 0022-3751
PURE UUID: aaa9d82c-11c5-43e9-87fb-4c7dd31c5b1b
ORCID for Geraldine Clough: ORCID iD orcid.org/0000-0002-6226-8964

Catalogue record

Date deposited: 05 Mar 2010
Last modified: 20 Jul 2019 01:16

Export record

Altmetrics

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×