Bone like resorbable silk based scaffolds for load bearing osteoregenerative applications
Bone like resorbable silk based scaffolds for load bearing osteoregenerative applications
Hydroxyapatite/silk biocompatible composites with unprecedented mechanical strength and toughness areproduced in a new process with theintegrated mineralization of macroporous silk fibroin scaffolds. Thebiomimetic bone-like composites areabsorbable and load-bearing with compressive strength, modulus, andtoughness comparable to the mechanical tolerances of cancellous bone.
biomineralization, biomedical materials, bone, silk, tissue engineering
75-78
Collins, Andrew M.
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Skaer, Nick J.V.
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Gheysens, Tom
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Knight, David
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Bertram, Caroline
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Roach, Helmtrud I.
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Oreffo, Richard O.C.
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Von-Aulock, Sonja
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Baris, Teodora
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Skinner, John
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Mann, Stephen
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January 2009
Collins, Andrew M.
72dddb4d-c1b7-4e9d-b483-ebeef9221394
Skaer, Nick J.V.
37579108-a63c-4a95-bca8-f24a7411bf48
Gheysens, Tom
3867f20e-3bbc-4fe6-904f-4444ae825efa
Knight, David
d1e4c844-1c07-4f6a-bd38-28f6338a7884
Bertram, Caroline
bd8d2058-c047-4dd6-a1f2-8191fcbe1b08
Roach, Helmtrud I.
ca2ff1f4-1ada-4c56-9097-cd27ca4d199e
Oreffo, Richard O.C.
ff9fff72-6855-4d0f-bfb2-311d0e8f3778
Von-Aulock, Sonja
f977e8f4-11c9-48bd-b2bd-ebaee0f7bc64
Baris, Teodora
92a399ba-bf83-442c-9788-5ca173114b27
Skinner, John
8470601d-cd27-4599-858b-870eea866c61
Mann, Stephen
1cbb2d4f-aee2-403c-9950-18bd388f02c0
Collins, Andrew M., Skaer, Nick J.V., Gheysens, Tom, Knight, David, Bertram, Caroline, Roach, Helmtrud I., Oreffo, Richard O.C., Von-Aulock, Sonja, Baris, Teodora, Skinner, John and Mann, Stephen
(2009)
Bone like resorbable silk based scaffolds for load bearing osteoregenerative applications.
Advanced Materials, 20 (1), .
(doi:10.1002/adma.200802239).
Abstract
Hydroxyapatite/silk biocompatible composites with unprecedented mechanical strength and toughness areproduced in a new process with theintegrated mineralization of macroporous silk fibroin scaffolds. Thebiomimetic bone-like composites areabsorbable and load-bearing with compressive strength, modulus, andtoughness comparable to the mechanical tolerances of cancellous bone.
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More information
Published date: January 2009
Keywords:
biomineralization, biomedical materials, bone, silk, tissue engineering
Identifiers
Local EPrints ID: 70341
URI: http://eprints.soton.ac.uk/id/eprint/70341
ISSN: 1521-4095
PURE UUID: 24bc765b-a2c1-4a77-8217-f0acff345d2f
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Date deposited: 28 Jan 2010
Last modified: 14 Mar 2024 02:43
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Contributors
Author:
Andrew M. Collins
Author:
Nick J.V. Skaer
Author:
Tom Gheysens
Author:
David Knight
Author:
Caroline Bertram
Author:
Helmtrud I. Roach
Author:
Sonja Von-Aulock
Author:
Teodora Baris
Author:
John Skinner
Author:
Stephen Mann
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