A hybrid form of cardiac resynchronisation therapy in patients with failing systemic right ventricles

Michael, Kevin A., Paisey, John R., Mayosi, Bongani M., Allen, Stuart, Sunni, Nadia S., Roberts, Paul R., Morgan, John M., Veldtman, Gruschen R. and Robinson, Stephen (2008) A hybrid form of cardiac resynchronisation therapy in patients with failing systemic right ventricles. Journal of Interventional Cardiac Electrophysiology, 23 (3), 229-233. (doi:10.1007/s10840-008-9296-0).

Abstract

Introduction Late systemic right ventricular (RV) dysfunction after atrial redirection surgery is common. Patients may require cardiac transplantation in early adulthood.
Methods We undertook cardiac resynchronisation (CRT)/defibrillator therapy in two patients as a bridge to transplantation.
Results Two males (aged 24, 110 kg and 26 years, 106 kg); having undergone a Mustard procedure for dextro-transposition of the great arteries at 7 and 6 months of age respectively, presented with impaired systemic RV function and New York Heart Association III symptoms. Both patients had dual chamber pacemakers in-situ for sinus bradycardia. Upgrade to CRT was performed by conserving the existing endocardial leads and placement of epicardial electrodes. One demonstrated sustained improvement over a 24 month follow-up period.
Conclusion A hybrid CRT strategy is feasible in patients with failing systemic RVs and pre-existent endocardial dual chamber pacemakers. Appropriate patient selection criteria and optimum lead placement, however, still needs further evaluation in this population.

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Contributors

Author: Stephen Robinson

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