Dietary counselling and food fortification in stable COPD: a randomised trial
Dietary counselling and food fortification in stable COPD: a randomised trial
Background: Malnutrition in chronic obstructive pulmonary disease (COPD) is associated with poor prognosis yet evidence to support the role of dietary counselling and food fortification is lacking.
Objective: To assess the impact of dietary counselling and food fortification on outcome in outpatients with COPD who are at risk of malnutrition.
Methods: Randomised, controlled trial (unblinded) in 59 outpatients with COPD (6 months INTERVENTION: 6 months follow-up). Intervention group received dietary counselling and advice on food fortification; controls received a dietary advice leaflet.
Outcome Measures: nutritional status, respiratory and skeletal muscle strength, respiratory function, perceived dyspnoea, activities of daily living (ADL) and quality of life.
Results: Intervention group consumed more energy (Difference 194 kcal/day; p = 0.02) and protein (Difference 11.8 g/day; p < 0.001) than controls. Intervention group gained weight during the intervention period and maintained weight during follow-up. Controls lost weight throughout the study. Significant differences were observed between groups in St. George's Respiratory Questionnaire Total Score (Difference 10.1; p = 0.02), Short Form-36 Health Change Score (Difference 19.2; p = 0.029) and Medical Research Council dyspnoea score (Difference 1.0; p = 0.03); difference in ADL score approached statistical significance (Difference 1.5; p = 0.06). No differences were observed between groups in respiratory function or skeletal and respiratory muscle strength. Improvements in some variables persisted for 6 months beyond the intervention period.
Conclusion: Dietary counselling and food fortification resulted in weight gain and improvements in outcome in nutritionally at risk outpatients with COPD, both during and beyond the intervention period
dietary, activity, united-kingdom, weight, skeletal muscle, follow-up, life, of-life, research, weight gain, quality of life, malnutrition, methods, strength, health, skeletal-muscle, protein, nutritional status, muscle, risk, prognosis, disease, muscle strength, trial, food
326-331
Weekes, C.E.
f518794c-67b6-46d1-b032-3f6a2c0937d3
Emery, P.W.
afae5586-16f0-4688-b499-3987092ef54c
Elia, M.
964bf436-e623-46d6-bc3f-5dd04c9ef4c1
2008
Weekes, C.E.
f518794c-67b6-46d1-b032-3f6a2c0937d3
Emery, P.W.
afae5586-16f0-4688-b499-3987092ef54c
Elia, M.
964bf436-e623-46d6-bc3f-5dd04c9ef4c1
Abstract
Background: Malnutrition in chronic obstructive pulmonary disease (COPD) is associated with poor prognosis yet evidence to support the role of dietary counselling and food fortification is lacking.
Objective: To assess the impact of dietary counselling and food fortification on outcome in outpatients with COPD who are at risk of malnutrition.
Methods: Randomised, controlled trial (unblinded) in 59 outpatients with COPD (6 months INTERVENTION: 6 months follow-up). Intervention group received dietary counselling and advice on food fortification; controls received a dietary advice leaflet.
Outcome Measures: nutritional status, respiratory and skeletal muscle strength, respiratory function, perceived dyspnoea, activities of daily living (ADL) and quality of life.
Results: Intervention group consumed more energy (Difference 194 kcal/day; p = 0.02) and protein (Difference 11.8 g/day; p < 0.001) than controls. Intervention group gained weight during the intervention period and maintained weight during follow-up. Controls lost weight throughout the study. Significant differences were observed between groups in St. George's Respiratory Questionnaire Total Score (Difference 10.1; p = 0.02), Short Form-36 Health Change Score (Difference 19.2; p = 0.029) and Medical Research Council dyspnoea score (Difference 1.0; p = 0.03); difference in ADL score approached statistical significance (Difference 1.5; p = 0.06). No differences were observed between groups in respiratory function or skeletal and respiratory muscle strength. Improvements in some variables persisted for 6 months beyond the intervention period.
Conclusion: Dietary counselling and food fortification resulted in weight gain and improvements in outcome in nutritionally at risk outpatients with COPD, both during and beyond the intervention period
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Published date: 2008
Keywords:
dietary, activity, united-kingdom, weight, skeletal muscle, follow-up, life, of-life, research, weight gain, quality of life, malnutrition, methods, strength, health, skeletal-muscle, protein, nutritional status, muscle, risk, prognosis, disease, muscle strength, trial, food
Organisations:
Dev Origins of Health & Disease
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Local EPrints ID: 70572
URI: http://eprints.soton.ac.uk/id/eprint/70572
ISSN: 0040-6376
PURE UUID: da2d535d-b0c4-4bd5-a783-a2357ddf679f
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Date deposited: 10 Feb 2010
Last modified: 13 Mar 2024 20:06
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Author:
C.E. Weekes
Author:
P.W. Emery
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