Chronic surgical site infection due to suture-associated polymicrobial biofilm

Kathju, Sandeep, Nistico, Laura, Hall-Stoodley, Luanne, Post, J. Christopher, Ehrlich, Garth D. and Stoodley, Paul (2009) Chronic surgical site infection due to suture-associated polymicrobial biofilm Surgical Infections, 10, (5), pp. 457-461. (doi:10.1089/sur.2008.062).


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Background: surgical site infection (SSI) is a common surgical complication; culture-negative SSI presents a particular problem in management.
Methods: examination of explanted foreign bodies (sutures) using confocal laser scanning microscopy (CLSM) and fluorescent in situ hybridization (FISH) after surgical exploration of a chronic culture-negative SSI.
Results: confocal microscopy (CM) demonstrated bacilli and cocci attached to the surface of the explanted sutures in a mixed biofilm. Florescent in situ hybridization confirmed that Staphylococci were components of the mixed biofilm. Removal of the foreign bodies (sutures) resolved the chronic infection.
Conclusion: chronic SSI can arise from underlying bacterial biofilms, which can invest implanted foreign bodies and associated soft tissue surfaces

Item Type: Article
Digital Object Identifier (DOI): doi:10.1089/sur.2008.062
Additional Information: The National Centre for Advanced Tribology at Southampton (nCATS)
ISSNs: 1096-2964 (print)
Related URLs:
ePrint ID: 71638
Date :
Date Event
November 2009Published
Date Deposited: 18 Dec 2009
Last Modified: 18 Apr 2017 21:02
Further Information:Google Scholar

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