The University of Southampton
University of Southampton Institutional Repository

Mode-switching: a new technique for electronically varying the agglomeration position in an acoustic particle manipulator

Glynne-Jones, Peter, Boltryk, Rosemary J., Harris, Nicholas R., Cranny, Andy W.J. and Hill, Martyn (2010) Mode-switching: a new technique for electronically varying the agglomeration position in an acoustic particle manipulator Ultrasonics, 50, (1), pp. 68-75. (doi:10.1016/j.ultras.2009.07.010).

Record type: Article


Acoustic radiation forces offer a means of manipulating particles within a fluid. Much interest in recent years has focussed on the use of radiation forces in microfluidic (or “lab on a chip”) devices. Such devices are well matched to the use of ultrasonic standing waves in which the resonant dimensions of the chamber are smaller than the ultrasonic wavelength in use. However, such devices have typically been limited to moving particles to one or two predetermined planes, whose positions are determined by acoustic pressure nodes/anti-nodes set up in the ultrasonic standing wave. In most cases devices have been designed to move particles to either the centre or (more recently) the side of a flow channel using ultrasonic frequencies that produce a half or quarter wavelength over the channel, respectively.
It is demonstrated here that by rapidly switching back and forth between half and quarter wavelength frequencies – mode-switching – a new agglomeration position is established that permits beads to be brought to any arbitrary point between the half and quarter-wave nodes. This new agglomeration position is effectively a position of stable equilibrium. This has many potential applications, particularly in cell sorting and manipulation. It should also enable precise control of agglomeration position to be maintained regardless of manufacturing tolerances, temperature variations, fluid medium characteristics and particle concentration

PDF Revised_Mode_Switch_Paper.pdf - Accepted Manuscript
Download (380kB)

More information

Submitted date: January 2008
Published date: January 2010
Keywords: ultrasonic particle manipulation, acoustic radiation force, layered resonators, microfluidics, mode-switching


Local EPrints ID: 71767
ISSN: 0041-624X
PURE UUID: 4b93f431-bfa8-48ab-8e1c-65326d7d87ab
ORCID for Peter Glynne-Jones: ORCID iD
ORCID for Nicholas R. Harris: ORCID iD
ORCID for Martyn Hill: ORCID iD

Catalogue record

Date deposited: 04 Jan 2010
Last modified: 18 Jul 2017 23:58

Export record


Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.