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Doppler ultrasound of the maternal uterine arteries: disappearance of abnormal waveforms and relation to birthweight and pregnancy outcome.

Doppler ultrasound of the maternal uterine arteries: disappearance of abnormal waveforms and relation to birthweight and pregnancy outcome.
Doppler ultrasound of the maternal uterine arteries: disappearance of abnormal waveforms and relation to birthweight and pregnancy outcome.
Background. To assess whether the gestation at which abnormal uterine artery waveforms disappear is related to birthweight and complications of pregnancy. Methods. A prospective study of outcome of pregnancy after a uterine artery Doppler screening program set in an inner city teaching hospital. One thousand five hundred and twenty-four consecutive women attending the Obstetric Department for a routine anomaly scan at between 19 and 21 weeks gestation had maternal uterine arteries assessed using color wave Doppler. Those women in whom the flow was deemed abnormal were recalled for a further scan at 24-26 weeks gestation. The main outcome measures were birthweight, gestation at delivery and incidence of pre eclampsia. Results. The women in whom the uterine artery blood flow was normal at 20 weeks had babies with significantly higher mean birthweight than those who normalized between 20 and 24-26 weeks gestation ('late normalizers') after adjustment for confounding factors; gestational age, maternal height, parity, ethnic group and smoking (mean difference=173 g, 95% confidence intervals 42 to 303 g). Conclusions. The timing of trophoblast invasion, as reflected by abnormal uterine artery waveforms, may have an effect on birthweight.
631-634
Campbell, Stuart
a34ed39f-49c0-48e1-a0a1-0932016ddbb8
Black, Rebecca S.
280e60bb-0d3a-46a1-a899-ac4c4764e763
Lees, Christoph C.
a10f7abc-1a55-4b57-903c-00e6a27a73d8
Armstrong, Valerie
938456a7-8104-4f41-bc1f-37b552c03ebc
Peacock, Janet L.
1cb1242c-7606-4f8e-86d0-d3cd2ceff782
Campbell, Stuart
a34ed39f-49c0-48e1-a0a1-0932016ddbb8
Black, Rebecca S.
280e60bb-0d3a-46a1-a899-ac4c4764e763
Lees, Christoph C.
a10f7abc-1a55-4b57-903c-00e6a27a73d8
Armstrong, Valerie
938456a7-8104-4f41-bc1f-37b552c03ebc
Peacock, Janet L.
1cb1242c-7606-4f8e-86d0-d3cd2ceff782

Campbell, Stuart, Black, Rebecca S., Lees, Christoph C., Armstrong, Valerie and Peacock, Janet L. (2000) Doppler ultrasound of the maternal uterine arteries: disappearance of abnormal waveforms and relation to birthweight and pregnancy outcome. Acta Obstetricia et Gynecologica Scandinavica, 79 (8), 631-634. (doi:10.1034/j.1600-0412.2000.079008631.x).

Record type: Article

Abstract

Background. To assess whether the gestation at which abnormal uterine artery waveforms disappear is related to birthweight and complications of pregnancy. Methods. A prospective study of outcome of pregnancy after a uterine artery Doppler screening program set in an inner city teaching hospital. One thousand five hundred and twenty-four consecutive women attending the Obstetric Department for a routine anomaly scan at between 19 and 21 weeks gestation had maternal uterine arteries assessed using color wave Doppler. Those women in whom the flow was deemed abnormal were recalled for a further scan at 24-26 weeks gestation. The main outcome measures were birthweight, gestation at delivery and incidence of pre eclampsia. Results. The women in whom the uterine artery blood flow was normal at 20 weeks had babies with significantly higher mean birthweight than those who normalized between 20 and 24-26 weeks gestation ('late normalizers') after adjustment for confounding factors; gestational age, maternal height, parity, ethnic group and smoking (mean difference=173 g, 95% confidence intervals 42 to 303 g). Conclusions. The timing of trophoblast invasion, as reflected by abnormal uterine artery waveforms, may have an effect on birthweight.

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Published date: August 2000

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Local EPrints ID: 72782
URI: https://eprints.soton.ac.uk/id/eprint/72782
PURE UUID: 61a0f109-79a2-45fa-b718-174613d24681

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Date deposited: 24 Feb 2010
Last modified: 09 Aug 2017 16:32

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