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Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate

Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate
Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate
Many adults are distressed by painful investigations or treatment, including venepuncture. The early effects of Eutectic Mixture of Local Anaesthetics (EMLA) 5%, on relief of pinprick pain in the antecubital area was investigated and compared with EMLA plus glyceryl trinitrate and with a placebo cream in 100 patients. Topical analgesia after application of EMLA developed within 5 min in 69% and within 10 min in 83% of those tested, significantly different from placebo, (P = 0.01).
0265-0215
17-20
Nott, M.R.
7877f33c-a324-4b80-8b58-975231302a00
Clemson, C.J.
bf7605e0-e7b7-47d1-9878-2b04a8e5b9ea
Peacock, J.L.
8362b3b1-458f-4152-936f-344ca1c7e0ba
Nott, M.R.
7877f33c-a324-4b80-8b58-975231302a00
Clemson, C.J.
bf7605e0-e7b7-47d1-9878-2b04a8e5b9ea
Peacock, J.L.
8362b3b1-458f-4152-936f-344ca1c7e0ba

Nott, M.R., Clemson, C.J. and Peacock, J.L. (1996) Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate. European Journal of Anaesthesiology, 13 (1), 17-20.

Record type: Article

Abstract

Many adults are distressed by painful investigations or treatment, including venepuncture. The early effects of Eutectic Mixture of Local Anaesthetics (EMLA) 5%, on relief of pinprick pain in the antecubital area was investigated and compared with EMLA plus glyceryl trinitrate and with a placebo cream in 100 patients. Topical analgesia after application of EMLA developed within 5 min in 69% and within 10 min in 83% of those tested, significantly different from placebo, (P = 0.01).

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Published date: January 1996
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Identifiers

Local EPrints ID: 72843
URI: http://eprints.soton.ac.uk/id/eprint/72843
ISSN: 0265-0215
PURE UUID: 0590ad85-dc94-4565-b2ef-07bda1046482

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Date deposited: 11 Mar 2010
Last modified: 07 Jan 2022 23:42

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Contributors

Author: M.R. Nott
Author: C.J. Clemson
Author: J.L. Peacock

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