Nott, M.R. and Peacock, J.L. (1990) Relief of injection pain in adults EMLA cream for 5 minutes before venepuncture. Anaesthesia, 45 (9), 772-774. (doi:10.1111/j.1365-2044.1990.tb14453.x).
Abstract
The effectiveness of skin anaesthesia after 5 minutes' topical application of a lignocaine-prilocaine cream was evaluated. One hundred and twenty patients estimated the pain of antecubital venepuncture both on a linear scale and verbally after use of the cream for either 5 or 60 minutes, a placebo cream or no treatment. Reported pain was significantly less after only 5 minutes of the lignocaine-prilocaine cream (p = 0.002). The cream can be used to relieve the pain of all routine injections.
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