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Excess mortality following hip fracture: a systematic epidemiological review

Excess mortality following hip fracture: a systematic epidemiological review
Excess mortality following hip fracture: a systematic epidemiological review
This systematic literature review has shown that patients experiencing hip fracture after low-impact trauma are at considerable excess risk for death compared with nonhip fracture/community control populations. The increased mortality risk may persist for several years thereafter, highlighting the need for interventions to reduce this risk.Patients experiencing hip fracture after low-impact trauma are at considerable risk for subsequent osteoporotic fractures and premature death. We conducted a systematic review of the literature to identify all studies that reported unadjusted and excess mortality rates for hip fracture. Although a lack of consistent study design precluded any formal meta-analysis or pooled analysis of the data, we have shown that hip fracture is associated with excess mortality (over and above mortality rates in nonhip fracture/community control populations) during the first year after fracture ranging from 8.4% to 36%. In the identified studies, individuals experienced an increased relative risk for mortality following hip fracture that was at least double that for the age-matched control population, became less pronounced with advancing age, was higher among men than women regardless of age, was highest in the days and weeks following the index fracture, and remained elevated for months and perhaps even years following the index fracture. These observations show that patients are at increased risk for premature death for many years after a fragility-related hip fracture and highlight the need to identify those patients who are candidates for interventions to reduce their risk
excess mortality, femoral neck fracture, fragility-related fracture, hip fracture, osteoporotic hip fracture, systematic review
0937-941X
1633-1650
Abrahamsen, B.
fee8b1eb-c267-4d2a-952a-d1b9f20d0125
van Staa, T.
7e263d59-ecc2-41f2-8b20-3f934d09c2c9
Ariely, R.
3452b849-cb21-4366-b918-f2af34242f8e
Olson, M.
f36f59b8-c114-460d-bd59-97c1bbf12453
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Abrahamsen, B.
fee8b1eb-c267-4d2a-952a-d1b9f20d0125
van Staa, T.
7e263d59-ecc2-41f2-8b20-3f934d09c2c9
Ariely, R.
3452b849-cb21-4366-b918-f2af34242f8e
Olson, M.
f36f59b8-c114-460d-bd59-97c1bbf12453
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6

Abrahamsen, B., van Staa, T., Ariely, R., Olson, M. and Cooper, C. (2009) Excess mortality following hip fracture: a systematic epidemiological review. Osteoporosis International, 20 (10), 1633-1650. (doi:10.1007/s00198-009-0920-3).

Record type: Article

Abstract

This systematic literature review has shown that patients experiencing hip fracture after low-impact trauma are at considerable excess risk for death compared with nonhip fracture/community control populations. The increased mortality risk may persist for several years thereafter, highlighting the need for interventions to reduce this risk.Patients experiencing hip fracture after low-impact trauma are at considerable risk for subsequent osteoporotic fractures and premature death. We conducted a systematic review of the literature to identify all studies that reported unadjusted and excess mortality rates for hip fracture. Although a lack of consistent study design precluded any formal meta-analysis or pooled analysis of the data, we have shown that hip fracture is associated with excess mortality (over and above mortality rates in nonhip fracture/community control populations) during the first year after fracture ranging from 8.4% to 36%. In the identified studies, individuals experienced an increased relative risk for mortality following hip fracture that was at least double that for the age-matched control population, became less pronounced with advancing age, was higher among men than women regardless of age, was highest in the days and weeks following the index fracture, and remained elevated for months and perhaps even years following the index fracture. These observations show that patients are at increased risk for premature death for many years after a fragility-related hip fracture and highlight the need to identify those patients who are candidates for interventions to reduce their risk

Full text not available from this repository.

More information

Published date: October 2009
Keywords: excess mortality, femoral neck fracture, fragility-related fracture, hip fracture, osteoporotic hip fracture, systematic review

Identifiers

Local EPrints ID: 72900
URI: https://eprints.soton.ac.uk/id/eprint/72900
ISSN: 0937-941X
PURE UUID: c5bbff53-13bc-4fc4-a67e-28c4275fc51f
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 24 Feb 2010
Last modified: 12 Nov 2019 01:57

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