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UK Renal registry 11th annual report, chapter 7 survival and causes of death of UK adults patients on renal replacement therapy in 2007: national and centre-specific analyses

UK Renal registry 11th annual report, chapter 7 survival and causes of death of UK adults patients on renal replacement therapy in 2007: national and centre-specific analyses
UK Renal registry 11th annual report, chapter 7 survival and causes of death of UK adults patients on renal replacement therapy in 2007: national and centre-specific analyses
Introduction: these analyses examine survival from the start of renal replacement therapy (RRT), based on the total incident UK dialysis population reported to the Registry, including the 21% who started on PD and the 5% who received a pre-emptive transplant. Survival of prevalent patients and changes in survival between 1997-2006 are reported. The article includes a discussion on the technical definition for the date of start of both PD and HD.
Methods: survival was calculated for both incident and prevalent patients on RRT and compared between the UK countries after adjustment for age. Survival of incident patients (starting during 2006) was calculated with and without a 90 day RRT start cut off. Survival of incident patients is shown with and without censoring at transplantation. Both the Kaplan-Meier and Cox adjusted models were used to calculate survival. Causes of death were analysed for both groups. Relative risk of death was calculated compared with the general UK population.
Results: the 2006 unadjusted 1 year after 90 day survival for patients starting RRT was 86%. In incident 18-64 year olds the unadjusted 1 year survival had risen from 85.9% in 1997 to 91.5% in 2006 and for those aged ges 65 it had risen from 63.8% to 72.9%. The age adjusted survival of prevalent dialysis patients rose from 85% in 2000 to 89% in 2007. Diabetic patient survival rose from 76.6% in 2000 to 84.0% in 2007. The relative risk of death on RRT compared with the general population was 30 at age 30 years compared with 3 at age 80 years. In the prevalent RRT dialysis population, cardiovascular disease accounted for 34% of deaths, infection 20% and treatment withdrawal 14%.
Conclusions: incident and prevalent patient survival on RRT in all the UK countries for all age ranges and also for patients with diabetes continued to improve. The relative risk of death on RRT compared with the general population has fallen since 2001. Death rates on dialysis in the UK remained lower than when compared with a similar aged population on dialysis in the USA
1660-8151
C113-C139
Ansell, David
9c009488-5612-4d05-9389-15dd3e238a7c
Roderick, Paul
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Hodsman, Alex
847b17ce-4e1b-4ab3-a752-64bf285c292c
Ford, Daniel
f06c18c8-784c-435d-9670-5c8ec653063c
Steenkamp, Retha
57994df9-d520-4a35-9f74-0dd0856b7ba9
Tomson, Charlie
a198db93-e002-4fc5-af35-4a3b2b8af444
Ansell, David
9c009488-5612-4d05-9389-15dd3e238a7c
Roderick, Paul
dbb3cd11-4c51-4844-982b-0eb30ad5085a
Hodsman, Alex
847b17ce-4e1b-4ab3-a752-64bf285c292c
Ford, Daniel
f06c18c8-784c-435d-9670-5c8ec653063c
Steenkamp, Retha
57994df9-d520-4a35-9f74-0dd0856b7ba9
Tomson, Charlie
a198db93-e002-4fc5-af35-4a3b2b8af444

Ansell, David, Roderick, Paul, Hodsman, Alex, Ford, Daniel, Steenkamp, Retha and Tomson, Charlie (2009) UK Renal registry 11th annual report, chapter 7 survival and causes of death of UK adults patients on renal replacement therapy in 2007: national and centre-specific analyses. Nephron, 111 (Supplement 1), C113-C139. (doi:10.1159/000209996).

Record type: Article

Abstract

Introduction: these analyses examine survival from the start of renal replacement therapy (RRT), based on the total incident UK dialysis population reported to the Registry, including the 21% who started on PD and the 5% who received a pre-emptive transplant. Survival of prevalent patients and changes in survival between 1997-2006 are reported. The article includes a discussion on the technical definition for the date of start of both PD and HD.
Methods: survival was calculated for both incident and prevalent patients on RRT and compared between the UK countries after adjustment for age. Survival of incident patients (starting during 2006) was calculated with and without a 90 day RRT start cut off. Survival of incident patients is shown with and without censoring at transplantation. Both the Kaplan-Meier and Cox adjusted models were used to calculate survival. Causes of death were analysed for both groups. Relative risk of death was calculated compared with the general UK population.
Results: the 2006 unadjusted 1 year after 90 day survival for patients starting RRT was 86%. In incident 18-64 year olds the unadjusted 1 year survival had risen from 85.9% in 1997 to 91.5% in 2006 and for those aged ges 65 it had risen from 63.8% to 72.9%. The age adjusted survival of prevalent dialysis patients rose from 85% in 2000 to 89% in 2007. Diabetic patient survival rose from 76.6% in 2000 to 84.0% in 2007. The relative risk of death on RRT compared with the general population was 30 at age 30 years compared with 3 at age 80 years. In the prevalent RRT dialysis population, cardiovascular disease accounted for 34% of deaths, infection 20% and treatment withdrawal 14%.
Conclusions: incident and prevalent patient survival on RRT in all the UK countries for all age ranges and also for patients with diabetes continued to improve. The relative risk of death on RRT compared with the general population has fallen since 2001. Death rates on dialysis in the UK remained lower than when compared with a similar aged population on dialysis in the USA

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Published date: 2009

Identifiers

Local EPrints ID: 72939
URI: http://eprints.soton.ac.uk/id/eprint/72939
ISSN: 1660-8151
PURE UUID: 48e5dd06-5a8b-4f26-89b1-17444f241fd5
ORCID for Paul Roderick: ORCID iD orcid.org/0000-0001-9475-6850

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Date deposited: 25 Feb 2010
Last modified: 14 Mar 2024 02:38

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Contributors

Author: David Ansell
Author: Paul Roderick ORCID iD
Author: Alex Hodsman
Author: Daniel Ford
Author: Retha Steenkamp
Author: Charlie Tomson

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