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The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22

The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22
The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22
Aim
The aim of this study was to develop a bone metastases module to supplement the European Organisation for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) or the EORTC QLQ-C15-PAL for patients with bone metastases.
Methods
Phases 1–2 of module development were conducted in Canada, Australia and Germany according to EORTC QOL group guidelines. Phase 3 was conducted in nine countries in seven languages.
Results
Sixty-one health-related quality of life (HRQOL) issues were generated from health care professionals (n = 152) and patients (n = 413). This resulted in a 22-item provisional module. Further testing in 170 patients from nine countries resulted in the EORTC QLQ-BM22 module, containing 22 items, conceptualised into both symptom scales, with five painful sites and three pain characteristics, and also functional scales, with eight functional interference and six psychosocial aspects.
Conclusion
This study provides a provisional comprehensive HRQOL measurement tool for future trials, which will continue to undergo further validation.
bone metastases, health-related quality of life, questionnaire, cancer, pain symptoms, eortc
0959-8049
1146-1152
Chow, Edward
d6237124-9931-4896-9e29-ae0c44b1d3d8
Hird, Amanda
a132bc23-5285-4dd2-a29f-0312e4031aaf
Velikova, Galina
60a74ab1-7fba-4d7a-8b40-598ed8398393
Johnson, Colin
e50aa9cd-8c61-4fe3-a0b3-f51cc3a6c74a
Dewolf, Linda
aaefa866-c159-4365-beb4-fc853ed1c2bf
Bezjak, Andrea
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Wu, Jackson
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Shafiq, Jesmin
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Sezer, Orhan
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Kardamakis, Dimitros
a9def1b4-c96c-4807-af2b-cb7044efd039
van der Linden, Yvette
a0fdb2f6-47fa-459a-ad09-9d0c17918a76
Ma, Brigette
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Castro, Monica
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Arnalot, Palmiro Foro
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Ahmedzai, Sam
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Clemons, Mark
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Hoskin, Peter
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Yee, Albert
833cdbc0-f788-43d0-b529-cac7815aff4b
Brundage, Michael
e6049d49-386b-4680-8161-90b9abb36a0f
Bottomley, Andrew
aa0c035f-f787-4557-8b12-9e757c413cd0
EORTC Quality of Life Group
Chow, Edward
d6237124-9931-4896-9e29-ae0c44b1d3d8
Hird, Amanda
a132bc23-5285-4dd2-a29f-0312e4031aaf
Velikova, Galina
60a74ab1-7fba-4d7a-8b40-598ed8398393
Johnson, Colin
e50aa9cd-8c61-4fe3-a0b3-f51cc3a6c74a
Dewolf, Linda
aaefa866-c159-4365-beb4-fc853ed1c2bf
Bezjak, Andrea
5b4519d0-8a36-44af-8e5b-2025a06abac4
Wu, Jackson
824868eb-0ba0-42a7-ae9f-d340c98c0e32
Shafiq, Jesmin
c3d58d72-110a-4930-876b-9760580f111a
Sezer, Orhan
0a946960-f7bd-4fac-bc69-d7a0784d4b04
Kardamakis, Dimitros
a9def1b4-c96c-4807-af2b-cb7044efd039
van der Linden, Yvette
a0fdb2f6-47fa-459a-ad09-9d0c17918a76
Ma, Brigette
6a2f8c04-71e5-4cdd-8309-8398bee73d2e
Castro, Monica
19352dfc-5e76-425a-927f-5d4d37737889
Arnalot, Palmiro Foro
8743c11e-cdea-4705-91b3-99d273d6f81a
Ahmedzai, Sam
4a6321f1-7ef0-430e-a7f6-a1b70b038599
Clemons, Mark
5e7f1feb-dff6-4f7d-beee-c24b8c8ba254
Hoskin, Peter
33fbd91a-06f5-4bb8-8b4c-41810bd71ed4
Yee, Albert
833cdbc0-f788-43d0-b529-cac7815aff4b
Brundage, Michael
e6049d49-386b-4680-8161-90b9abb36a0f
Bottomley, Andrew
aa0c035f-f787-4557-8b12-9e757c413cd0

Chow, Edward, Hird, Amanda, Velikova, Galina, Johnson, Colin, Dewolf, Linda, Bezjak, Andrea, Wu, Jackson, Shafiq, Jesmin, Sezer, Orhan, Kardamakis, Dimitros, van der Linden, Yvette, Ma, Brigette, Castro, Monica, Arnalot, Palmiro Foro, Ahmedzai, Sam, Clemons, Mark, Hoskin, Peter, Yee, Albert, Brundage, Michael and Bottomley, Andrew , EORTC Quality of Life Group (2009) The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire for patients with bone metastases: the EORTC QLQ-BM22. European Journal of Cancer, 45 (7), 1146-1152. (doi:10.1016/j.ejca.2008.11.013).

Record type: Article

Abstract

Aim
The aim of this study was to develop a bone metastases module to supplement the European Organisation for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) or the EORTC QLQ-C15-PAL for patients with bone metastases.
Methods
Phases 1–2 of module development were conducted in Canada, Australia and Germany according to EORTC QOL group guidelines. Phase 3 was conducted in nine countries in seven languages.
Results
Sixty-one health-related quality of life (HRQOL) issues were generated from health care professionals (n = 152) and patients (n = 413). This resulted in a 22-item provisional module. Further testing in 170 patients from nine countries resulted in the EORTC QLQ-BM22 module, containing 22 items, conceptualised into both symptom scales, with five painful sites and three pain characteristics, and also functional scales, with eight functional interference and six psychosocial aspects.
Conclusion
This study provides a provisional comprehensive HRQOL measurement tool for future trials, which will continue to undergo further validation.

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More information

Published date: May 2009
Keywords: bone metastases, health-related quality of life, questionnaire, cancer, pain symptoms, eortc

Identifiers

Local EPrints ID: 73010
URI: https://eprints.soton.ac.uk/id/eprint/73010
ISSN: 0959-8049
PURE UUID: 6b211906-5c06-4b38-b9cc-1842f1ee6998

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Date deposited: 26 Feb 2010
Last modified: 19 Jul 2019 23:41

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Contributors

Author: Edward Chow
Author: Amanda Hird
Author: Galina Velikova
Author: Colin Johnson
Author: Linda Dewolf
Author: Andrea Bezjak
Author: Jackson Wu
Author: Jesmin Shafiq
Author: Orhan Sezer
Author: Dimitros Kardamakis
Author: Yvette van der Linden
Author: Brigette Ma
Author: Monica Castro
Author: Palmiro Foro Arnalot
Author: Sam Ahmedzai
Author: Mark Clemons
Author: Peter Hoskin
Author: Albert Yee
Author: Michael Brundage
Author: Andrew Bottomley

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