McKie, A.T., Naftalin, R.J. and Powrie, W.
Mechanical aspects of rabbit fecal dehydration
American Journal of Physiology. Gastrointestinal and Liver Physiology, 258, .
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The hydrostatic pressure required to reduce the water content of rabbit feces in an odometer from greater than 80 to less than 65% was approximately 5 atm. This pressure was unaffected by raising the temperature from 20 to 37 degrees C. It became progressively more difficult to dehydrate feces as consolidation occurred, as is evident from the significant (P less than 0.001) reduction in the fecal consolidation coefficient (Co) from 1.76 +/- 0.25 X 10(-6) (n = 4) to 1.35 +/- 0.093 X 10(-7) m2/s (n = 4) and the fecal fluid permeability coefficient (k) from 4.10 +/- 0.51 X 10(-8) (n = 4) to 1.42 +/- 0.12 X 10(-10) m/s (n = 4), concomitant with the reduction in fecal water content. The results suggest that rabbit hard feces are unlikely to be produced, under physiological conditions, by mechanical pressure exerted by the wall of the colon or by a prolonged retention time of hard feces by the distal colon. The hypertonic absorbate (1,000 mosmol/kg) produced by rabbit descending colon is of sufficient magnitude to overcome the fecal resistance to dehydration.
||McKie A T, Naftalin R J, Powrie W., (1990). "Mechanical aspects of rabbit fecal dehydration." American Journal of Physiology (gastrointest. Liver Physiol.), 258, G391-394
||11 Mar 2010
||18 Apr 2017 20:42
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