A review of techniques for adhesion prevention after gynaecological surgery
A review of techniques for adhesion prevention after gynaecological surgery
Purpose of review: to explore recent developments in the techniques used for the prevention of adhesion formation after gynaecological surgery as well as the current evidence for existing agents and techniques.
Recent findings: recent developments are promising new biomaterials such as polyvinyl alcohol gel and hyaluronic acid cross-linked with various agents such as nanoparticles. Other substances that have recently received attention include novel anti-inflammatory agents, Oxiplex (FzioMed, Inc., San Luis Obispo, California, USA), sildenafil, statins and also, there has been some renewed interest in dextran. Furthermore, the combination of barrier and pharmacological agents has led to the introduction of interesting new hybrid systems. Finally, despite the development of many novel antiadhesion agents, good surgical technique remains the mainstay of adhesion prevention.
Summary: there is preliminary evidence to support the use of hyaluronic acid, although the best preparation is yet to be determined. The use of icodextrin, Interceed (Ethicon Inc, Somerville, New Jersey, USA) and Oxiplex seem to be justified by the currently available data. The results of interesting new technologies such as the use of hybrid systems and new forms of biomaterials are awaited.
345-352
Metwally, Mostafa
2e4e46cc-45f6-4428-9696-2382412040b1
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Li, Tin Chiu
ea5b25bc-c0b2-406c-8a6b-f711a68966b5
August 2008
Metwally, Mostafa
2e4e46cc-45f6-4428-9696-2382412040b1
Cheong, Ying
4efbba2a-3036-4dce-82f1-8b4017952c83
Li, Tin Chiu
ea5b25bc-c0b2-406c-8a6b-f711a68966b5
Metwally, Mostafa, Cheong, Ying and Li, Tin Chiu
(2008)
A review of techniques for adhesion prevention after gynaecological surgery.
Current Opinion in Obstetrics and Gynecology, 20 (4), .
(doi:10.1097/GCO.0b013e3283073a6c).
(PMID:18660685)
Abstract
Purpose of review: to explore recent developments in the techniques used for the prevention of adhesion formation after gynaecological surgery as well as the current evidence for existing agents and techniques.
Recent findings: recent developments are promising new biomaterials such as polyvinyl alcohol gel and hyaluronic acid cross-linked with various agents such as nanoparticles. Other substances that have recently received attention include novel anti-inflammatory agents, Oxiplex (FzioMed, Inc., San Luis Obispo, California, USA), sildenafil, statins and also, there has been some renewed interest in dextran. Furthermore, the combination of barrier and pharmacological agents has led to the introduction of interesting new hybrid systems. Finally, despite the development of many novel antiadhesion agents, good surgical technique remains the mainstay of adhesion prevention.
Summary: there is preliminary evidence to support the use of hyaluronic acid, although the best preparation is yet to be determined. The use of icodextrin, Interceed (Ethicon Inc, Somerville, New Jersey, USA) and Oxiplex seem to be justified by the currently available data. The results of interesting new technologies such as the use of hybrid systems and new forms of biomaterials are awaited.
This record has no associated files available for download.
More information
Published date: August 2008
Identifiers
Local EPrints ID: 76225
URI: http://eprints.soton.ac.uk/id/eprint/76225
ISSN: 1040-872X
PURE UUID: 3f4c5d39-bd54-45af-bb31-764c3cd845a8
Catalogue record
Date deposited: 15 Mar 2010
Last modified: 14 Mar 2024 02:53
Export record
Altmetrics
Contributors
Author:
Mostafa Metwally
Author:
Tin Chiu Li
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics
