Integrated optical immunofluorescence sensor for environmental monitoring
Integrated optical immunofluorescence sensor for environmental monitoring
We have demonstrated a regenerable waveguide fluorescence sensor for environmental monitoring. Characterisation of the sensor as a detector of the pesticide 2,4 dichlorophenoxyacetic acid in water is presented. A binding inhibition assay, using fluorescent Cy5.5 dye-labelled antibodies, was monitored at the modified surface of the glass waveguide to detect the target analyte. Incorporation of a thin high-index film at the waveguide surface enhanced device sensitivity.
Harris, R.D.
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Quigley, G.R.
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Wilkinson, J.S.
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Klotz, A.
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Barzen, C.
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Brecht, A.
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Gauglitz, G.
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Abuknesha, R.A.
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1998
Harris, R.D.
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Quigley, G.R.
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Wilkinson, J.S.
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Klotz, A.
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Barzen, C.
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Brecht, A.
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Gauglitz, G.
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Abuknesha, R.A.
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Harris, R.D., Quigley, G.R., Wilkinson, J.S., Klotz, A., Barzen, C., Brecht, A., Gauglitz, G. and Abuknesha, R.A.
(1998)
Integrated optical immunofluorescence sensor for environmental monitoring.
Biosensors '98, Berlin, Germany.
03 - 05 Jun 1998.
Record type:
Conference or Workshop Item
(Paper)
Abstract
We have demonstrated a regenerable waveguide fluorescence sensor for environmental monitoring. Characterisation of the sensor as a detector of the pesticide 2,4 dichlorophenoxyacetic acid in water is presented. A binding inhibition assay, using fluorescent Cy5.5 dye-labelled antibodies, was monitored at the modified surface of the glass waveguide to detect the target analyte. Incorporation of a thin high-index film at the waveguide surface enhanced device sensitivity.
Text
1708
- Author's Original
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Published date: 1998
Venue - Dates:
Biosensors '98, Berlin, Germany, 1998-06-03 - 1998-06-05
Identifiers
Local EPrints ID: 76617
URI: http://eprints.soton.ac.uk/id/eprint/76617
PURE UUID: 74358d3e-bc17-44d0-afe1-fbb09aa4f82a
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Date deposited: 11 Mar 2010
Last modified: 14 Mar 2024 02:32
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Contributors
Author:
R.D. Harris
Author:
G.R. Quigley
Author:
A. Klotz
Author:
C. Barzen
Author:
A. Brecht
Author:
G. Gauglitz
Author:
R.A. Abuknesha
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