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Integrated optical immunofluorescence sensor for environmental monitoring

Integrated optical immunofluorescence sensor for environmental monitoring
Integrated optical immunofluorescence sensor for environmental monitoring
We have demonstrated a regenerable waveguide fluorescence sensor for environmental monitoring. Characterisation of the sensor as a detector of the pesticide 2,4 dichlorophenoxyacetic acid in water is presented. A binding inhibition assay, using fluorescent Cy5.5 dye-labelled antibodies, was monitored at the modified surface of the glass waveguide to detect the target analyte. Incorporation of a thin high-index film at the waveguide surface enhanced device sensitivity.
Harris, R.D.
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Quigley, G.R.
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Wilkinson, J.S.
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Klotz, A.
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Barzen, C.
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Brecht, A.
1b34ee2a-ada5-48ec-923a-f385835fbc83
Gauglitz, G.
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Abuknesha, R.A.
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Harris, R.D.
e972b676-3335-44cd-b6e8-0dae17c550c3
Quigley, G.R.
7d719dee-8822-4f48-9a29-52c7bc000a27
Wilkinson, J.S.
73483cf3-d9f2-4688-9b09-1c84257884ca
Klotz, A.
6295d51a-2cbd-4ebd-ac4f-de919e314636
Barzen, C.
e57de777-3451-4b75-b44a-937e8a317e5b
Brecht, A.
1b34ee2a-ada5-48ec-923a-f385835fbc83
Gauglitz, G.
119b102d-52db-4eba-81c0-0bdd5a16f1e7
Abuknesha, R.A.
f8222e58-66df-41c8-912f-1a11b2c3db6d

Harris, R.D., Quigley, G.R., Wilkinson, J.S., Klotz, A., Barzen, C., Brecht, A., Gauglitz, G. and Abuknesha, R.A. (1998) Integrated optical immunofluorescence sensor for environmental monitoring. Biosensors '98, Germany. 03 - 05 Jun 1998.

Record type: Conference or Workshop Item (Paper)

Abstract

We have demonstrated a regenerable waveguide fluorescence sensor for environmental monitoring. Characterisation of the sensor as a detector of the pesticide 2,4 dichlorophenoxyacetic acid in water is presented. A binding inhibition assay, using fluorescent Cy5.5 dye-labelled antibodies, was monitored at the modified surface of the glass waveguide to detect the target analyte. Incorporation of a thin high-index film at the waveguide surface enhanced device sensitivity.

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More information

Published date: 1998
Venue - Dates: Biosensors '98, Germany, 1998-06-03 - 1998-06-05

Identifiers

Local EPrints ID: 76617
URI: https://eprints.soton.ac.uk/id/eprint/76617
PURE UUID: 74358d3e-bc17-44d0-afe1-fbb09aa4f82a
ORCID for J.S. Wilkinson: ORCID iD orcid.org/0000-0003-4712-1697

Catalogue record

Date deposited: 11 Mar 2010
Last modified: 06 Jun 2018 13:19

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