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Enzymatic disassembly of DNA-gold nanostructures

Enzymatic disassembly of DNA-gold nanostructures
Enzymatic disassembly of DNA-gold nanostructures
The efficient digestion of nanoparticle assemblies connected by DNA linkers is demonstrated using a number of complementary methods (enzymatic cleavage with EcoRI is shown in the scheme). The efficiency of digestion is dependent on the design of the DNA linker. The ability to manipulate DNA enzymatically is important in the development of hierarchical chemical methods of nanoscale assembly.
DNA, gold, nanoparticles, nanostructures, restriction enzymes
1613-6810
590-594
Kanaras, Antonios G.
667ecfdc-7647-4bd8-be03-a47bf32504c7
Wang, Zhenxin
3282751e-a88e-4a77-ba94-0a35c1bd62b5
Brust, Mathias
b1f6f579-7c99-4529-824d-8c182c8c525d
Cosstick, Richard
c863fc03-bcbe-4e09-8896-805aa919afee
Bates, Andrew D.
c366b8ff-fd00-4273-903d-f22442ba0e09
Kanaras, Antonios G.
667ecfdc-7647-4bd8-be03-a47bf32504c7
Wang, Zhenxin
3282751e-a88e-4a77-ba94-0a35c1bd62b5
Brust, Mathias
b1f6f579-7c99-4529-824d-8c182c8c525d
Cosstick, Richard
c863fc03-bcbe-4e09-8896-805aa919afee
Bates, Andrew D.
c366b8ff-fd00-4273-903d-f22442ba0e09

Kanaras, Antonios G., Wang, Zhenxin, Brust, Mathias, Cosstick, Richard and Bates, Andrew D. (2007) Enzymatic disassembly of DNA-gold nanostructures. Small, 3 (4), 590-594. (doi:10.1002/smll.200600494).

Record type: Article

Abstract

The efficient digestion of nanoparticle assemblies connected by DNA linkers is demonstrated using a number of complementary methods (enzymatic cleavage with EcoRI is shown in the scheme). The efficiency of digestion is dependent on the design of the DNA linker. The ability to manipulate DNA enzymatically is important in the development of hierarchical chemical methods of nanoscale assembly.

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More information

Submitted date: 13 September 2006
Published date: 22 February 2007
Keywords: DNA, gold, nanoparticles, nanostructures, restriction enzymes
Organisations: Quantum, Light & Matter Group

Identifiers

Local EPrints ID: 79547
URI: https://eprints.soton.ac.uk/id/eprint/79547
ISSN: 1613-6810
PURE UUID: 28507818-6440-4903-ba67-69f86bedcf33
ORCID for Antonios G. Kanaras: ORCID iD orcid.org/0000-0002-9847-6706

Catalogue record

Date deposited: 26 Mar 2010
Last modified: 31 Jul 2019 00:39

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Contributors

Author: Zhenxin Wang
Author: Mathias Brust
Author: Richard Cosstick
Author: Andrew D. Bates

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