Items where Division is "Current Faculties > Faculty of Engineering and Physical Sciences > Chemistry and Chemical Engineering > Chemical Biology, Diagnostics and Therapeutics
Chemistry and Chemical Engineering > Chemical Biology, Diagnostics and Therapeutics" and Year is 2024
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Number of items: 28.
Identification and development of cyclic peptide inhibitors of Hypoxia Inducible Factors 1 and 2 that disrupt hypoxia-response signaling in cancer cells - Andrew T. Ball, Soran Mohammed, Cyrielle Doigneaux, Reece M. Gardner, James W. Easton, Steven Turner, Jonathan W. Essex, Garry Pairaudeau and Ali Tavassoli
Type: Article
| 2024
| Item availability restricted.
Reversibly Tuning the Viscosity of Peptide-Based Solutions Using Visible Light - Simona Bianco, Laura Wimberger and Yael Ben-Tal
Type: Article
| 2024
Markers of adipose tissue fibrogenesis associate with clinically significant liver fibrosis and are unchanged by synbiotic treatment in patients with NAFLD - Josh Bilson, Carolina J. Oquendo, James Read, Eleonora Scorletti, Paul R. Afolabi, Jenny Lord, Laure B. Bindels, Giovanni Targher, Sumeet Mahajan, Diana Baralle, Philip C. Calder, Christopher D. Byrne and Jaswinder K. Sethi
Type: Article
| 2024
Holistic vibrational spectromics assessment of human cartilage for osteoarthritis diagnosis - Hiroki Cook, Anna Crisford, Konstantinos Bourdakos, Doug Dunlop, Richard O.C. Oreffo and Sumeet Mahajan
Type: Article
| 2024
Mechanisms of SARS-CoV-2 inactivation using UVC laser radiation - George Devitt, Peter B. Johnson, Niall Hanrahan, Simon I.R. Lane, Magdalena C. Vidale, Bhavwanti Sheth, Joel D. Allen, Maria V. Humbert, Cosma M. Spalluto, Rodolphe C. Herve, Karl Staples, Jonathan J. West, Robert Forster, Nullin Divecha, Chris McCormick, Max Crispin, Nils Hempler, Graeme P.A. Malcolm and Sumeet Mahajan
Type: Article
| 2024
Synthesis, biophysical and biological evaluation of splice-switching oligonucleotides with multiple LNA-phosphothiotriester backbones - Debashis Dhara, Alyssa C. Hill, Abinaya Ramesh, Matthew J.A. Wood, Afaf H. El-Sagheer and Tom Brown
Type: Article
| 2024
Synthesis of N-alkyl-3-[2-oxoquinolin-1(2H)-yl]propanoic acid derivatives and related compounds: cytotoxicity and EGFR inhibition of some propanamide derivatives - Samir M. El Rayes, Ibrahim A.I. Ali, Walid Fathalla, Mohamed A. Ghanem, Afaf H. El-Sagheer and Mohamed S. Nafie
Type: Article
| 2024
Single-cell high-precision ablation using nanosecond-pulsed thulium-doped fiber laser - Matthew D. Gerard, Hiroki Marius Oswald Cook, James A. Read, Ibrahim H. Abughazaleh, Panuwat Srisamran, Siddhi Chugh, Sijing Liang, Qiang Fu, Richard O.C. Oreffo, David J. Richardson, Sumeet Mahajan and Lin Xu
Type: Article
| 2024
Type: Dataset
| 2024
| University of Southampton
Hydrogel-based standards for single and multiphoton imaging at depth - Fizza Haseeb, Konstantinos N. Bourdakos, Ewan Forsyth, Kerry Setchfield, Alistair Gorman, Seshasailam Venkateswaran, Amanda J. Wright, Sumeet Mahajan and Mark Bradley
Type: Conference or Workshop Item
| 2024
| SPIE
Introduction to the themed collection in honour of Professor Christian Leumann - Marcel Hollenstein and Eugen Stulz
Type: Editorial
| 2024
| Item availability restricted.
Type: Dataset
| 2024
| University of Southampton
Modular and automated synthesis of oligonucleotide-small molecule conjugates for cathepsin B mediated traceless release of payloads - Cheng Jin, Siqi Li, Katherine Vallis, Afaf El-Sagheer and Tom Brown
Type: Article
| 2024
Distributable, metabolic PET reporting of tuberculosis - R.M. Naseer Khan, Yong-Mo Ahn and Gwendolyn A. Marriner
Type: Article
| 2024
Hypoxia-inducing transcription factors: architects of tumorigenesis and targets for anticancer drug discovery - Alexander McDermott and Ali Tavassoli
Type: Article
| 2024
Next generation SICLOPPS screening for the identification of inhibitors of the HIF-1α/HIF-1β protein–protein interaction - Alexander McDermott, Leonie M. Windeln, Jacob S.D. Valentine, Andrew D. Foster and Ali Tavassoli
Type: Article
| 2024
Type: Dataset
| 2024
| University of Southampton
Type: Dataset
| 2024
| University of Southampton
Exploring 2-sulfonylpyrimidine warheads as acrylamide surrogates for targeted covalent inhibition: a BTK story - Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E. Wales, Raji E. Joseph, Amy H. Andreotti, Jonathan C. Strefford, Graham Packham and Matthias G.J. Baud
Type: Article
| 2024
Type: Dataset
| 2024
| University of Southampton
A platform approach to cleavable macrocycles for the controlled disassembly of mechanically caged molecules - Abed Saady, Georgia K. Malcolm, Matthew P. Fitzpatrick, Noel GM Pairault, Graham J. Tizzard, Soran Mohammed, Ali Tavassoli and Stephen M. Goldup
Type: Article
| 2024
Correlative geochemical imaging of Desmophyllum dianthus reveals biomineralisation strategy as a key coral vital effect - Christopher D. Standish, Jacob Trend, Jacob Kleboe, Thomas B. Chalk, Sumeet Mahajan, J. Andy Milton, Tessa Page, Laura F. Robinson, Joseph A. Stewart and Gavin L. Foster
Type: Article
| 2024
Droplet microfluidics for time-resolved serial crystallography - Jack Stubbs, Theo Hornsey, Niall Hanrahan, Luis Blay Esteban, Rachel Bolton, Martin Malý, Shibom Basu, Julien Orlans, Daniele de Sanctis, Jung-uk Shim, Patrick D. Shaw Stewart, Allen M. Orville, Ivo Tews and Jonathan West
Type: Article
| 2024
Artificial intelligence-enhanced analysis of genomic DNA visualized with nanoparticle-tagged peptides under electron microscopy - Priyannth Ramasami Sundharbaabu, Junhyuck Chang, Yunchul Kim, Youmin Shim, Byoungsang Lee, Chanyoung Noh, Sujung Heo, Seung Seo Lee, Sang-Hee Shim, Kwang-il Lim, Kyubong Jo and Jung Heon Lee
Type: Article
| 2024
Double-clad antiresonant hollow-core fiber and its comparison with other fibers for multiphoton micro-endoscopy - Marzanna Szwaj, Ian A. Davidson, Peter B. Johnson, Greg Jasion, Yongmin Jung, Seyed Reza Sandoghchi, Krzysztof P. Herdzik, Konstantinos N. Bourdakos, Natalie V. Wheeler, Hans Christian Mulvad, David J. Richardson, Francesco Poletti and Sumeet Mahajan
Type: Article
| 2024
Type: Dataset
| 2024
| University of Southampton
Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs - Gangshun Yi, Mingda Ye, Loic Carrique, Afaf El-Sagheer, Tom Brown, Chris J. Norbury, Peijun Zhang and Robert J.C. Gilbert
Type: Article
| 2024
Synthesis and properties of oligonucleotides containing LNA-sulfamate and sulfamide backbone linkages - Belma Zengin Kurt, Debashis Dhara, Afaf H. El-Sagheer and Tom Brown
Type: Article
| 2024