Items where Division is "Current Faculties > Faculty of Medicine > NIHR Southampton Clinical Research Facility" and Year is 2025
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Number of items: 19.
Efficacy, immunogenicity, and safety of a next-generation mRNA-1283 COVID-19 vaccine compared with the mRNA-1273 vaccine (NextCOVE): results from a phase 3, randomised, observer-blind, active-controlled trial - Spyros Chalkias, Patrick Dennis, Dena Petersen, Krishnakumar Radhakrishnan, Leroy Vaughan, Reem Handforth, Alexandra Rossi, Rahnuma Wahid, Darin K. Edwards, Jing Feng, Weiping Deng, Honghong Zhou, Elizabeth De Windt, Veronica Urdaneta, Yamuna Paila, Bethany Girard, Saul N. Faust, Stephen R. Walsh, Catherine A. Cosgrove, Jacqueline Miller and Rituparna Das
Type: Article
| 2025
Changes in carriage and serotype diversity of Streptococcus pneumoniae and other respiratory pathobionts in the UK between pre-PCV13 (2006-10), early-PCV13 (2010-12) and late-PCV13 (2012-23) periods - David W. Cleary, Rebecca Anderson, Jessica Jones, Rebecca Gladstone, Karen L. Osman, Vanessa T. Devine, Denise E. Morris, Alex J.J. Lister, Stephen Gomer, Rebecca E. Hocknell, Emily J. Dineen, James Campling, Maria Lahuerta, Kyla Hayford, Jo Southern, Brad D. Gessner, Stephanie W. Lo, Stephen D. Bentley, Saul Faust and Stuart C. Clarke
Type: Article
| 2025
Pertussis antibody responses in infants born to mothers vaccinated at different time points in pregnancy - Olwenn Daniel, Sashank Srikanth, Paul Clarke, Kirsty Le Doare, Paul T. Heath, Christine E. Jones, Tim Scorrer, Matthew Snape and Anna Calvert
Type: Article
| 2025
Antibody in breastmilk following pertussis vaccination in three-time windows in pregnancy - Olwenn Daniel, Myles Loughnan, Miranda Quenby, Krina Chawla, Vanessa Greening, Paul Heath, Christine E. Jones, Asma Khalil, Laxmee Ramkhelawon, Anna Calvert and Kirsty Le Doare
Type: Article
| 2025
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Type: Article
| 2025
Type: Article
| 2025
Safety and humoral immunogenicity of the ChAdOx1 nCoV-19 vaccine administered as a fourth dose booster following two doses of ChAdOx1 nCoV-19 and a third dose of BNT162b2 (COV009) : a prospective cohort study - Shuo Feng, Sagida Bibi and Parvinder K. Aley
Type: Article
| 2025
The impact of congenital cytomegalovirus infection among families and caregivers: a qualitative analysis of responses to a public consultation on newborn screening in the UK - Rosamund Greiner, Sarah Dewar, Christine E Jones, Marthe Le Prevost, Tushna Vandrevala, Cristina Visintin and Heather Bailey
Type: Article
| 2025
Type: Article
| 2025
| Item availability restricted.
Identification and antimicrobial resistance profiling of Pseudomonas aeruginosa using multi-excitation Raman spectroscopy and computational analytics - Callum Highmore, Niall Hanrahan, Yoshiki Cook, Ysanne Pritchard, Adam Lister, Kirsty Cooper, George Devitt, Alasdair P.S. Munro, Saul N. Faust, Sumeet Mahajan and Jeremy S. Webb
Type: Article
| 2025
Immunizing Pregnant Women and Infants (IMPRINT) Network: building and sustaining an interdisciplinary network tackling the complex challenges of vaccination in pregnancy and early life - Beate Kampmann, Christine E . Jones and Hannah M.A. Faber
Type: Article
| 2025
Type: Article
| 2025
A template tool for the evaluation of vaccines for emerging pathogens to be used for pregnant and breast-feeding women - Flor M. Munoz, Beate Kampmann, Andy Stergachis, Manu Chaudhary, Clare L. Cutland, Asma Khalil, Angela Gentile, Christine Jones, Helen Marshall, Esperanca Sevene, Delese Mimi Darko, Geeta Swamy, Terri B. Hyde, Gerald Voss and Ajoke Sobanjo Ter Muelen
Type: Article
| 2025
Development of a multicentre cohort study to understand the role of MRI and ultrasound in the diagnosis of acute haematogenous bone and joint infection in children (the PIC Bone study) a study protocol - Marie-Caroline Nogaro, Stuart Hartshorn, Mariea Brady, Amaka Offiah, Saul Faust, Gregory Firth, Jie Ma, Paula Dhiman, Joanna O'Mahoney, Loretta Davies, Catherine Spowart, Amy Moscrop, Bridget Young, Catrin Tudur-Smith, Gary Collins, Daniel C. Perry and Tim Theologis
Type: Article
| 2025
Optimising outcomes for adults with cystic fibrosis taking CFTR modulators by individualising care: personalised data linkage to understand treatment optimisation (PLUTO), a novel clinical framework - Robert D. Sandler, Alan Anderson and Tracy Barnett
Type: Review
| 2025
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Requirements and special considerations for drug trials with children across six jurisdictions: 2. Ethics review in the regulatory approval process - Breanne Stewart, Pirkko Nykanen and Gunter F. Egger
Type: Article
| 2025
R21 in Matrix-M adjuvant in UK malaria-naive adult men and non-pregnant women aged 18–45 years: an open-label, partially blinded, phase 1–2a controlled human malaria infection study - Navin Venkatraman, Daniel Silman, Duncan Bellamy, Lisa Stockdale, Georgina Bowyer, Nick J. Edwards, Oliver Griffiths, Fernando Ramos Lopez, Jonathan Powlson, Catherine Mair, Pedro M. Folegatti, Mehreen S. Datoo, Richard Morter, Angela M. Minassian, Ian Poulton, Katharine A. Collins, Florian Brod, Philip Angell-Manning, Eleanor Berrie, Nathan Brendish, Greg Glenn, Louis Fries, Jake Baum, Andrew M. Blagborough, Rachel Roberts, Alison M. Lawrie, Brian Angus, David J.M. Lewis, Saul N. Faust, Katie J. Ewer and Adrian V.S. Hill
Type: Article
| 2025
Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT - Cherry Ann Waldron, Philip Pallmann, Simon Schoenbuchner, Debbie Harris, Lucy Brookes-Howell, Céu Mateus, Jolanta Bernatoniene, Katrina Cathie, Saul N. Faust, Josie Henley, Lucy Hinds, Kerry Hood, Chao Huang, Sarah Jones, Sarah Kotecha, Sarah Milosevic, Helen Nabwera, Sanjay Patel, Stéphane Paulus, Colin V.E. Powell, Jenny Preston, Huasheng Xiang, Emma Thomas-Jones and Enitan D. Carrol
Type: Article
| 2025
Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH): a pragmatic, multicentre, open-label, two-arm, individually randomised, controlled trial - Cherry-Ann Waldron, Philip Pallmann and Simon Schoenbuchner
Type: Article
| 2025