Integrated systems for rapid point of care (PoC) blood cell analysis
Integrated systems for rapid point of care (PoC) blood cell analysis
Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.
1249-1255
van Berkel, Cees
148b8dd1-6357-4308-81af-1ee11d287e99
Gwyer, James D.
a996644a-37b0-4bc6-b47e-4e553f7c92a7
Deane, Steve
1eaa8cd2-4ac0-4a96-9e38-5396137d22e3
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Holloway, Judith
f22f45f3-6fc8-4a4c-bc6c-24add507037c
Hollis, Veronica
98fb298c-a05a-4ddc-9b4e-500762bfa007
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
7 April 2011
van Berkel, Cees
148b8dd1-6357-4308-81af-1ee11d287e99
Gwyer, James D.
a996644a-37b0-4bc6-b47e-4e553f7c92a7
Deane, Steve
1eaa8cd2-4ac0-4a96-9e38-5396137d22e3
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Holloway, Judith
f22f45f3-6fc8-4a4c-bc6c-24add507037c
Hollis, Veronica
98fb298c-a05a-4ddc-9b4e-500762bfa007
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
van Berkel, Cees, Gwyer, James D., Deane, Steve, Green, Nicolas G, Holloway, Judith, Hollis, Veronica and Morgan, Hywel
(2011)
Integrated systems for rapid point of care (PoC) blood cell analysis.
Lab on a Chip, 11 (7), .
(doi:10.1039/C0LC00587H).
(PMID:21331413)
Abstract
Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.
Text
J56_vanBerkel_Gwyer_Deane_Green_Holloway_Hollis_Morgan_Lab_On_A_Chip_2011.pdf
- Other
More information
Published date: 7 April 2011
Organisations:
Infection Inflammation & Immunity, Electronics & Computer Science, Engineering Sciences
Identifiers
Local EPrints ID: 181025
URI: http://eprints.soton.ac.uk/id/eprint/181025
ISSN: 1473-0197
PURE UUID: f1ff08a2-db3b-4d9c-bcd8-83d83360e7bf
Catalogue record
Date deposited: 13 Apr 2011 10:20
Last modified: 15 Mar 2024 03:20
Export record
Altmetrics
Contributors
Author:
Cees van Berkel
Author:
James D. Gwyer
Author:
Steve Deane
Author:
Nicolas G Green
Author:
Hywel Morgan
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics