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Integrated systems for rapid point of care (PoC) blood cell analysis

Record type: Article

Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.

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Citation

van Berkel, Cees, Gwyer, James D., Deane, Steve, Green, Nicolas G, Holloway, Judith, Hollis, Veronica and Morgan, Hywel (2011) Integrated systems for rapid point of care (PoC) blood cell analysis Lab on a Chip, 11, (7), pp. 1249-1255. (doi:10.1039/C0LC00587H). (PMID:21331413).

More information

Published date: 7 April 2011
Organisations: Infection Inflammation & Immunity, Electronics & Computer Science, Engineering Sciences

Identifiers

Local EPrints ID: 181025
URI: http://eprints.soton.ac.uk/id/eprint/181025
ISSN: 1473-0197
PURE UUID: f1ff08a2-db3b-4d9c-bcd8-83d83360e7bf
ORCID for Nicolas G Green: ORCID iD orcid.org/0000-0001-9230-4455
ORCID for Judith Holloway: ORCID iD orcid.org/0000-0002-2268-3071
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676

Catalogue record

Date deposited: 13 Apr 2011 10:20
Last modified: 18 Jul 2017 12:00

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