Integrated systems for rapid point of care (PoC) blood cell analysis


van Berkel, Cees, Gwyer, James D., Deane, Steve, Green, Nicolas G, Holloway, Judith, Hollis, Veronica and Morgan, Hywel (2011) Integrated systems for rapid point of care (PoC) blood cell analysis Lab on a Chip, 11, (7), pp. 1249-1255. (doi:10.1039/C0LC00587H). (PMID:21331413).

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Description/Abstract

Counting the different subpopulations of cells in a fingerprick of human blood is important for a number of clinical point-of-care (PoC) applications. It is a challenge to demonstrate the integration of sample preparation and detection techniques in a single platform. In this paper we demonstrate a generic microfluidic platform that combines sample processing and characterisation and enumeration in a single, integrated system. Results of microfluidic 3-part differential leukocyte (granulocyte, lymphocyte and monocyte) counts, together with erythrocyte and thrombocyte (platelet) counts, in human blood are shown and corroborated with results from hospital clinical laboratory analysis.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1039/C0LC00587H
ISSNs: 1473-0197 (print)
Related URLs:
Subjects:
Organisations: Electronics & Computer Science
ePrint ID: 181025
Date :
Date Event
7 April 2011Published
Date Deposited: 13 Apr 2011 10:20
Last Modified: 18 Apr 2017 02:30
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/181025

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