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Evolving gene regulatory networks for cellular morphogenesis

Evolving gene regulatory networks for cellular morphogenesis
Evolving gene regulatory networks for cellular morphogenesis
The generation of pattern and form in a developing organism results from a combination of interacting processes, guided by a programme en- coded in its genome. The unfolding of this programme involves a complex interplay of gene regulation and inter-cellular signalling, as well as the mechanical processes of cell growth, division and movement. In this study we present an integrated modelling framework for simulating multicellular morphogenesis that includes plausible models of both genetic and cellular processes, using leaf morphogenesis as an example. We present results of an experiment designed to investigate the contribution that genetic control of cell growth and division makes to the performance of a developing system.
gene regulatory networks, development, morphogenesis
978-981-256-615-7
239-252
World Scientific
Rudge, T
d50efe88-d673-447f-8c6a-5cc2836d1749
Geard, N L
c8d726f5-9161-4c9e-9f3f-d87d4ceed9fa
Abbass, H
Bossamaier, T
Wiles, J
Rudge, T
d50efe88-d673-447f-8c6a-5cc2836d1749
Geard, N L
c8d726f5-9161-4c9e-9f3f-d87d4ceed9fa
Abbass, H
Bossamaier, T
Wiles, J

Rudge, T and Geard, N L (2005) Evolving gene regulatory networks for cellular morphogenesis. Abbass, H, Bossamaier, T and Wiles, J (eds.) In Recent Advances in Artificial Life, Second Australian Conference, ACAL 2005, Proceedings. World Scientific. pp. 239-252 .

Record type: Conference or Workshop Item (Paper)

Abstract

The generation of pattern and form in a developing organism results from a combination of interacting processes, guided by a programme en- coded in its genome. The unfolding of this programme involves a complex interplay of gene regulation and inter-cellular signalling, as well as the mechanical processes of cell growth, division and movement. In this study we present an integrated modelling framework for simulating multicellular morphogenesis that includes plausible models of both genetic and cellular processes, using leaf morphogenesis as an example. We present results of an experiment designed to investigate the contribution that genetic control of cell growth and division makes to the performance of a developing system.

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More information

Published date: 2005
Additional Information: Event Dates: 5-6 December, 2005
Venue - Dates: The Second Australian Conference on Artificial Life, Sydney, Australia, 2005-12-05 - 2005-12-06
Keywords: gene regulatory networks, development, morphogenesis
Organisations: Electronics & Computer Science

Identifiers

Local EPrints ID: 264086
URI: http://eprints.soton.ac.uk/id/eprint/264086
ISBN: 978-981-256-615-7
PURE UUID: 02832619-aba5-4269-8a3e-f9c372bab9ab

Catalogue record

Date deposited: 25 May 2007
Last modified: 14 Mar 2024 07:42

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Contributors

Author: T Rudge
Author: N L Geard
Editor: H Abbass
Editor: T Bossamaier
Editor: J Wiles

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