A gene regulatory network for cell differentiation in Caenorhabditis elegans
A gene regulatory network for cell differentiation in Caenorhabditis elegans
Biological development is a remarkably complex process. A single cell, in an appropriate environment, contains enough information to produce a wide variety of specialised cell types, whose spatial and temporal dynamics interact to form intricately detailed patterns and behaviour. Much of the complexity of a developing system lies in the dynamics of gene regulation that occur within each cell. We used a simple recurrent network to model the process of gene regulation and evolved systems that were able to generate the first four cell divisions of the C. elegans cell lineage tree with a high degree of accuracy.
gene regulation
86-100
University of New South Wales
Geard, N L
c8d726f5-9161-4c9e-9f3f-d87d4ceed9fa
Wiles, J
4b566453-d3c4-441a-97bd-404c378d1f67
2003
Geard, N L
c8d726f5-9161-4c9e-9f3f-d87d4ceed9fa
Wiles, J
4b566453-d3c4-441a-97bd-404c378d1f67
Geard, N L and Wiles, J
(2003)
A gene regulatory network for cell differentiation in Caenorhabditis elegans.
Abbass, H and Wiles, J
(eds.)
In Proceedings of the First Australian Conference on Artificial Life.
University of New South Wales.
.
Record type:
Conference or Workshop Item
(Paper)
Abstract
Biological development is a remarkably complex process. A single cell, in an appropriate environment, contains enough information to produce a wide variety of specialised cell types, whose spatial and temporal dynamics interact to form intricately detailed patterns and behaviour. Much of the complexity of a developing system lies in the dynamics of gene regulation that occur within each cell. We used a simple recurrent network to model the process of gene regulation and evolved systems that were able to generate the first four cell divisions of the C. elegans cell lineage tree with a high degree of accuracy.
Text
acal-grn.pdf
- Other
More information
Published date: 2003
Venue - Dates:
The First Australian Conference on Artificial Life, Canberra, Australia, 2003-01-01
Keywords:
gene regulation
Organisations:
Electronics & Computer Science
Identifiers
Local EPrints ID: 264204
URI: http://eprints.soton.ac.uk/id/eprint/264204
PURE UUID: a77d779c-cc09-46fc-918d-9a1579a95a25
Catalogue record
Date deposited: 19 Jun 2007
Last modified: 14 Mar 2024 07:44
Export record
Contributors
Author:
N L Geard
Author:
J Wiles
Editor:
H Abbass
Editor:
J Wiles
Download statistics
Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.
View more statistics