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A DNA based five-state switch with programmed reversibility

A DNA based five-state switch with programmed reversibility
A DNA based five-state switch with programmed reversibility
A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.
1359-7345
11088-11090
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
Burns, Jonathan R.
648a50f5-bcca-4989-8de3-60cc582b7ed9
Singleton, Daniel
6c251bf3-8ca7-478d-8870-b39705b1c5fc
Preus, Soren
4436a185-554a-4445-910f-ba0fcd31810f
Stulz, Eugen
9a6c04cf-32ca-442b-9281-bbf3d23c622d
Burns, Jonathan R.
648a50f5-bcca-4989-8de3-60cc582b7ed9
Singleton, Daniel
6c251bf3-8ca7-478d-8870-b39705b1c5fc
Preus, Soren
4436a185-554a-4445-910f-ba0fcd31810f

Stulz, Eugen, Burns, Jonathan R., Singleton, Daniel and Preus, Soren (2012) A DNA based five-state switch with programmed reversibility. Chemical Communications, 48, 11088-11090. (doi:10.1039/C2CC35799B).

Record type: Article

Abstract

A programmable switch based on a DNA hairpin loop is functionalised with a rigid or flexible porphyrin or FAM and TAMRA FRET pair, which provides insight into the restructuring of the hairpin as well as porphyrin–porphyrin coupling. The switch contains five discrete states which can be accessed independently and followed by real-time spectroscopy, opening the way to a quinary computing code.

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Published date: 24 September 2012

Identifiers

Local EPrints ID: 343738
URI: http://eprints.soton.ac.uk/id/eprint/343738
DOI: doi:10.1039/C2CC35799B
ISSN: 1359-7345
PURE UUID: a7ebe50b-68a0-4d8d-a550-85f8ef4998f8
ORCID for Eugen Stulz: ORCID iD orcid.org/0000-0002-5302-2276

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Date deposited: 09 Oct 2012 14:07
Last modified: 15 Mar 2024 03:26

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Contributors

Author: Eugen Stulz ORCID iD
Author: Jonathan R. Burns
Author: Daniel Singleton
Author: Soren Preus

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