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Treatment-related problems experienced by cancer patients undergoing chemotherapy: a scoping review

Treatment-related problems experienced by cancer patients undergoing chemotherapy: a scoping review
Treatment-related problems experienced by cancer patients undergoing chemotherapy: a scoping review
Cancer patients undergoing chemotherapy experience a range of treatment-related problems, and variations in prevalence exist between treatment centres. A scoping review was undertaken to map reported rates of problem prevalence in the literature. This will inform development of a patient-reported outcome measure (PROM) to monitor prevalence and severity of problems over time and assist service providers optimise supportive care provision. Two databases (Embase and Medline) were searched from 2002 to 2013. Fifty one published papers and conference abstracts reporting problem prevalence rates were identified. The papers reported 98 different problems, from which a typology of 27 problem domains was developed, including both physical symptoms and psychosocial issues. The problem domains most often studied were nausea, vomiting and fatigue. This review reflects the chemotherapy-associated problems to which researchers attach the most importance. The range in reported prevalence across studies was very broad (e.g. nausea: 9–74%), with even less frequently studied problems showing high prevalence in some studies (e.g. gynaecological problems: up to 94%). The wide variation in prevalence and range of problems experienced raises challenges for PROM development. Patients should therefore be involved in consensus exercises to assist selection of items to ensure any instrument is complete and robust
cancer, chemotherapy, symptoms, quality of life, supportive care
0961-5423
1-13
Wagland, R.
16a44dcc-29cd-4797-9af2-41ef87f64d08
Richardson, A.
3db30680-aa47-43a5-b54d-62d10ece17b7
Armes, J.
162c2c72-239b-425d-af92-77c0b5c7a432
Hankins, M.
ce4b7d68-3320-4af4-9dd7-3537a4b07219
Lennan, E.
f0457b7d-c5b2-4584-a622-63d2bea62b3b
Griffiths, P.
ac7afec1-7d72-4b83-b016-3a43e245265b
Wagland, R.
16a44dcc-29cd-4797-9af2-41ef87f64d08
Richardson, A.
3db30680-aa47-43a5-b54d-62d10ece17b7
Armes, J.
162c2c72-239b-425d-af92-77c0b5c7a432
Hankins, M.
ce4b7d68-3320-4af4-9dd7-3537a4b07219
Lennan, E.
f0457b7d-c5b2-4584-a622-63d2bea62b3b
Griffiths, P.
ac7afec1-7d72-4b83-b016-3a43e245265b

Wagland, R., Richardson, A., Armes, J., Hankins, M., Lennan, E. and Griffiths, P. (2014) Treatment-related problems experienced by cancer patients undergoing chemotherapy: a scoping review. European Journal of Cancer Care, 1-13. (doi:10.1111/ecc.12246). (PMID:25296389)

Record type: Article

Abstract

Cancer patients undergoing chemotherapy experience a range of treatment-related problems, and variations in prevalence exist between treatment centres. A scoping review was undertaken to map reported rates of problem prevalence in the literature. This will inform development of a patient-reported outcome measure (PROM) to monitor prevalence and severity of problems over time and assist service providers optimise supportive care provision. Two databases (Embase and Medline) were searched from 2002 to 2013. Fifty one published papers and conference abstracts reporting problem prevalence rates were identified. The papers reported 98 different problems, from which a typology of 27 problem domains was developed, including both physical symptoms and psychosocial issues. The problem domains most often studied were nausea, vomiting and fatigue. This review reflects the chemotherapy-associated problems to which researchers attach the most importance. The range in reported prevalence across studies was very broad (e.g. nausea: 9–74%), with even less frequently studied problems showing high prevalence in some studies (e.g. gynaecological problems: up to 94%). The wide variation in prevalence and range of problems experienced raises challenges for PROM development. Patients should therefore be involved in consensus exercises to assist selection of items to ensure any instrument is complete and robust

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Accepted/In Press date: 18 August 2014
e-pub ahead of print date: 8 October 2014
Published date: 8 October 2014
Keywords: cancer, chemotherapy, symptoms, quality of life, supportive care
Organisations: Faculty of Health Sciences

Identifiers

Local EPrints ID: 374565
URI: http://eprints.soton.ac.uk/id/eprint/374565
ISSN: 0961-5423
PURE UUID: 56b909dd-662b-47d7-8505-5251c81d6325
ORCID for R. Wagland: ORCID iD orcid.org/0000-0003-1825-7587
ORCID for A. Richardson: ORCID iD orcid.org/0000-0003-3127-5755
ORCID for P. Griffiths: ORCID iD orcid.org/0000-0003-2439-2857

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Date deposited: 20 Feb 2015 16:44
Last modified: 15 Mar 2024 03:37

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Contributors

Author: R. Wagland ORCID iD
Author: A. Richardson ORCID iD
Author: J. Armes
Author: M. Hankins
Author: E. Lennan
Author: P. Griffiths ORCID iD

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