Exercise intervention in people with cancer undergoing adjuvant cancer treatment following surgery: a systematic review
Exercise intervention in people with cancer undergoing adjuvant cancer treatment following surgery: a systematic review
Background
Remaining physically active during and after cancer treatment is known to improve associated adverse effects, improve overall survival and reduce the probability of relapse. This systematic review addresses the question: is an exercise training programme beneficial in people with cancer undergoing adjuvant cancer treatment following surgery.
Methods
A systematic database search of Embase, Ovid, Medline without Revisions, SPORTDiscus, Web of Science, Cochrane Library and ClinicalTrials.gov for any randomised controlled trials (RCT) or non-RCT addressing the effect of an exercise training programme in those having adjuvant cancer treatment following surgery was conducted.
Results
The database search yielded 6489 candidate abstracts of which 94 references included the required terms. A total of 17 articles were included in this review. Exercise training is safe and feasible in the adjuvant setting and furthermore may improve measures of physical fitness and health related quality of life (HRQoL).
Conclusion
This is the first systematic review on exercise training interventions in people with cancer undergoing adjuvant cancer treatment following surgery. Due to the lack of adequately powered RCTs in this area, it remains unclear whether exercise training in this context improves clinical outcomes other physical fitness and HRQoL. It remains unclear what is the optimal timing of initiation of an exercise programme and what are the best combinations of elements within an exercise training programme to optimise training efficacy. Furthermore, it is unclear if initiating such exercise programmes at cancer diagnosis may have a long-lasting effect on physically activity throughout the subsequent life course.
cancer, surgery, adjuvant cancer treatment, exercise intervention
1-13
Loughney, L.
9c3e7db1-468b-405c-b32f-cedd9cc251fe
West, M.A.
98b67e58-9875-4133-b236-8a10a0a12c04
Kemp, G.J.
8732e1d2-a7c0-45a3-b69b-7649b517cd5f
Grocott, M.P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Jack, S.
d824ec2e-e92f-4e68-8fa5-953dfec46208
2015
Loughney, L.
9c3e7db1-468b-405c-b32f-cedd9cc251fe
West, M.A.
98b67e58-9875-4133-b236-8a10a0a12c04
Kemp, G.J.
8732e1d2-a7c0-45a3-b69b-7649b517cd5f
Grocott, M.P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Jack, S.
d824ec2e-e92f-4e68-8fa5-953dfec46208
Loughney, L., West, M.A., Kemp, G.J., Grocott, M.P.W. and Jack, S.
(2015)
Exercise intervention in people with cancer undergoing adjuvant cancer treatment following surgery: a systematic review.
European Journal of Surgical Oncology, .
(doi:10.1016/j.ejso.2015.08.153).
(PMID:26358569)
Abstract
Background
Remaining physically active during and after cancer treatment is known to improve associated adverse effects, improve overall survival and reduce the probability of relapse. This systematic review addresses the question: is an exercise training programme beneficial in people with cancer undergoing adjuvant cancer treatment following surgery.
Methods
A systematic database search of Embase, Ovid, Medline without Revisions, SPORTDiscus, Web of Science, Cochrane Library and ClinicalTrials.gov for any randomised controlled trials (RCT) or non-RCT addressing the effect of an exercise training programme in those having adjuvant cancer treatment following surgery was conducted.
Results
The database search yielded 6489 candidate abstracts of which 94 references included the required terms. A total of 17 articles were included in this review. Exercise training is safe and feasible in the adjuvant setting and furthermore may improve measures of physical fitness and health related quality of life (HRQoL).
Conclusion
This is the first systematic review on exercise training interventions in people with cancer undergoing adjuvant cancer treatment following surgery. Due to the lack of adequately powered RCTs in this area, it remains unclear whether exercise training in this context improves clinical outcomes other physical fitness and HRQoL. It remains unclear what is the optimal timing of initiation of an exercise programme and what are the best combinations of elements within an exercise training programme to optimise training efficacy. Furthermore, it is unclear if initiating such exercise programmes at cancer diagnosis may have a long-lasting effect on physically activity throughout the subsequent life course.
Text
__userfiles.soton.ac.uk_Library_SLAs_Work_for_ALL's_Work_for_ePrints_Accepted Manuscripts_Loughney_Exercise.pdf
- Accepted Manuscript
Text
Adjuvant SR_Final _17_01_2015_LL
- Accepted Manuscript
More information
Accepted/In Press date: 4 August 2015
e-pub ahead of print date: 29 August 2015
Published date: 2015
Keywords:
cancer, surgery, adjuvant cancer treatment, exercise intervention
Organisations:
Cancer Sciences, Clinical & Experimental Sciences
Identifiers
Local EPrints ID: 383084
URI: http://eprints.soton.ac.uk/id/eprint/383084
ISSN: 0748-7983
PURE UUID: 4ec5913f-eea2-4845-b133-6f00addbcd50
Catalogue record
Date deposited: 22 Oct 2015 10:40
Last modified: 15 Mar 2024 03:58
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Contributors
Author:
L. Loughney
Author:
G.J. Kemp
Author:
S. Jack
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