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UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016

UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016
UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap in adults during the acute phase of the disease.

The document aims to:

Offer an appraisal of all relevant literature up to February 2016, focusing on any key developments.

Address important, practical clinical questions relating to the primary guideline objective, i.e. accurate diagnosis and identification of cases and suitable treatment.

Provide guideline recommendations.

Discuss areas of uncertainty, potential developments and future directions.
stevens–johnson syndrome, toxic epidermal necrolysis, drug hypersensitivity, management, guidelines
1748-6815
e119-e153
Creamer, D.
2b3a4b47-b45e-4731-9145-7d3e29db77e7
Walsh, S.A.
02345ebe-442a-4933-97c7-b8c4e5066940
Dziewulski, P.
8df40638-78aa-4b28-b6ab-14c461d0db43
Exton, L.S.
c94046ec-8caa-4c7e-b585-d2d3d75169a9
Lee, H.Y.
43b45c39-d1f0-4778-a049-883b907bf48d
Dart, J.K.G.
3ef67709-35ce-40c9-ba32-f63126b102cc
Setterfield, J.
f22ca2d8-e009-4465-9d6e-85df4b966981
Bunker, C.B.
6fb468f6-cb4d-44f9-b38a-40b9983ab50f
Ardern-Jones, M.R.
7ac43c24-94ab-4d19-ba69-afaa546bec90
Watson, K.M.T.
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Wong, G.A.E.
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Philippidou, M.
d0eac4cc-08be-4385-8f87-51e5f14744f5
Vercueil, A.
f42ceb8f-903a-4273-b0bf-ff9429996695
Martin, R.V.
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Williams, G.
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Shah, M.
c89fdf39-3923-475c-9365-d51d86888d6c
Brown, D.
066e8669-5678-4f7c-96eb-e8e29a9a4cfb
Williams, P.
f9438e1e-9cc3-4dfb-9246-a2cc2405182d
Mohd Mustapa, M.F.
e3b198b9-0a9b-4366-bffa-f1b273636649
Smith, C.H.
facfe4e0-b59a-4764-9d70-de1d1e65ebf6
Creamer, D.
2b3a4b47-b45e-4731-9145-7d3e29db77e7
Walsh, S.A.
02345ebe-442a-4933-97c7-b8c4e5066940
Dziewulski, P.
8df40638-78aa-4b28-b6ab-14c461d0db43
Exton, L.S.
c94046ec-8caa-4c7e-b585-d2d3d75169a9
Lee, H.Y.
43b45c39-d1f0-4778-a049-883b907bf48d
Dart, J.K.G.
3ef67709-35ce-40c9-ba32-f63126b102cc
Setterfield, J.
f22ca2d8-e009-4465-9d6e-85df4b966981
Bunker, C.B.
6fb468f6-cb4d-44f9-b38a-40b9983ab50f
Ardern-Jones, M.R.
7ac43c24-94ab-4d19-ba69-afaa546bec90
Watson, K.M.T.
b06e7cc3-3ce6-437b-9a4d-56e4ea0856b1
Wong, G.A.E.
e01a315b-9be4-48de-a344-75c118d14092
Philippidou, M.
d0eac4cc-08be-4385-8f87-51e5f14744f5
Vercueil, A.
f42ceb8f-903a-4273-b0bf-ff9429996695
Martin, R.V.
77ece675-be93-4c38-a96c-8b0b95d307ed
Williams, G.
7e38985a-981b-4f64-8c33-9c0854a199e3
Shah, M.
c89fdf39-3923-475c-9365-d51d86888d6c
Brown, D.
066e8669-5678-4f7c-96eb-e8e29a9a4cfb
Williams, P.
f9438e1e-9cc3-4dfb-9246-a2cc2405182d
Mohd Mustapa, M.F.
e3b198b9-0a9b-4366-bffa-f1b273636649
Smith, C.H.
facfe4e0-b59a-4764-9d70-de1d1e65ebf6

Creamer, D., Walsh, S.A., Dziewulski, P., Exton, L.S., Lee, H.Y., Dart, J.K.G., Setterfield, J., Bunker, C.B., Ardern-Jones, M.R., Watson, K.M.T., Wong, G.A.E., Philippidou, M., Vercueil, A., Martin, R.V., Williams, G., Shah, M., Brown, D., Williams, P., Mohd Mustapa, M.F. and Smith, C.H. (2016) UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults 2016. Journal of Plastic, Reconstructive & Aesthetic Surgery, 69 (6), e119-e153. (doi:10.1016/j.bjps.2016.01.034). (PMID:27287213)

Record type: Article

Abstract

The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap in adults during the acute phase of the disease.

The document aims to:

Offer an appraisal of all relevant literature up to February 2016, focusing on any key developments.

Address important, practical clinical questions relating to the primary guideline objective, i.e. accurate diagnosis and identification of cases and suitable treatment.

Provide guideline recommendations.

Discuss areas of uncertainty, potential developments and future directions.

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More information

Accepted/In Press date: 14 January 2016
e-pub ahead of print date: 7 June 2016
Published date: June 2016
Keywords: stevens–johnson syndrome, toxic epidermal necrolysis, drug hypersensitivity, management, guidelines
Organisations: Faculty of Medicine

Identifiers

Local EPrints ID: 397259
URI: http://eprints.soton.ac.uk/id/eprint/397259
DOI: doi:10.1016/j.bjps.2016.01.034
ISSN: 1748-6815
PURE UUID: 91d02d60-37e4-4d5c-9507-edd3845192c4
ORCID for M.R. Ardern-Jones: ORCID iD orcid.org/0000-0003-1466-2016

Catalogue record

Date deposited: 30 Jun 2016 08:23
Last modified: 15 Mar 2024 05:41

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Contributors

Author: D. Creamer
Author: S.A. Walsh
Author: P. Dziewulski
Author: L.S. Exton
Author: H.Y. Lee
Author: J.K.G. Dart
Author: J. Setterfield
Author: C.B. Bunker
Author: M.R. Ardern-Jones ORCID iD
Author: K.M.T. Watson
Author: G.A.E. Wong
Author: M. Philippidou
Author: A. Vercueil
Author: R.V. Martin
Author: G. Williams
Author: M. Shah
Author: D. Brown
Author: P. Williams
Author: M.F. Mohd Mustapa
Author: C.H. Smith

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