The University of Southampton
University of Southampton Institutional Repository

Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice

Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice
Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice
This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other pharmacological modalities used in this indication. Effectiveness of intra-articular hyaluronic acid has also been highlighted based on ‘real-life' data, together with the clinical benefit of systematic repeated treatment cycles, and the influence of the molecular weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful to clinicians when making personalized care decisions.
0004-3591
1-37
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Rannou, F.
ddca60fd-e7fe-4f90-89d4-dae0639dcec4
Richette, P.
81184c8f-3602-4bf4-93ca-dc720d42f6c1
Bruyere, O.
9c455ea4-7f77-407f-ab5a-ecb571db8245
Al-Daghri, N.
21272a0a-ffb4-4380-a04f-e4d9cc2e7f3c
Altman, R.D.
5d8e4c70-1fc1-4c90-ba0c-807a37f38b1d
Luisa-Brandi, M.
84db3ab4-0c25-47ca-a587-1350cfd29d61
Collaud Basset, S.
ca710e3a-1b6b-42df-b0b5-fd12c4146d85
Herrero-Beaumont, G.
514e463a-d5b5-400d-aa6b-1b0ac2f720dc
Migliore, A.
27718882-2496-42ce-bed3-d3e5ed5301b6
Pavelka, K.
d2dc7e87-7ebd-4a11-825f-e3f46d364df4
Uebelhart, D.
cb224382-2034-431a-af69-f32b1ba1d004
Reginster, J.Y.
4083b457-5347-4ece-a53e-af19c8868c42
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Rannou, F.
ddca60fd-e7fe-4f90-89d4-dae0639dcec4
Richette, P.
81184c8f-3602-4bf4-93ca-dc720d42f6c1
Bruyere, O.
9c455ea4-7f77-407f-ab5a-ecb571db8245
Al-Daghri, N.
21272a0a-ffb4-4380-a04f-e4d9cc2e7f3c
Altman, R.D.
5d8e4c70-1fc1-4c90-ba0c-807a37f38b1d
Luisa-Brandi, M.
84db3ab4-0c25-47ca-a587-1350cfd29d61
Collaud Basset, S.
ca710e3a-1b6b-42df-b0b5-fd12c4146d85
Herrero-Beaumont, G.
514e463a-d5b5-400d-aa6b-1b0ac2f720dc
Migliore, A.
27718882-2496-42ce-bed3-d3e5ed5301b6
Pavelka, K.
d2dc7e87-7ebd-4a11-825f-e3f46d364df4
Uebelhart, D.
cb224382-2034-431a-af69-f32b1ba1d004
Reginster, J.Y.
4083b457-5347-4ece-a53e-af19c8868c42

Cooper, C., Rannou, F., Richette, P., Bruyere, O., Al-Daghri, N., Altman, R.D., Luisa-Brandi, M., Collaud Basset, S., Herrero-Beaumont, G., Migliore, A., Pavelka, K., Uebelhart, D. and Reginster, J.Y. (2017) Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice. Arthritis & Rheumatism, 1-37. (doi:10.1002/acr.23204). (PMID:28118523)

Record type: Article

Abstract

This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other pharmacological modalities used in this indication. Effectiveness of intra-articular hyaluronic acid has also been highlighted based on ‘real-life' data, together with the clinical benefit of systematic repeated treatment cycles, and the influence of the molecular weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful to clinicians when making personalized care decisions.

Text
AR submitted clean copy.docx - Accepted Manuscript
Download (335kB)

More information

Accepted/In Press date: 17 January 2017
e-pub ahead of print date: 24 January 2017
Organisations: MRC Life-Course Epidemiology Unit

Identifiers

Local EPrints ID: 405185
URI: http://eprints.soton.ac.uk/id/eprint/405185
ISSN: 0004-3591
PURE UUID: 0ed59918-1b8c-4caa-9471-d29fcbdfd0fc
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 30 Jan 2017 10:25
Last modified: 18 Mar 2024 05:08

Export record

Altmetrics

Contributors

Author: C. Cooper ORCID iD
Author: F. Rannou
Author: P. Richette
Author: O. Bruyere
Author: N. Al-Daghri
Author: R.D. Altman
Author: M. Luisa-Brandi
Author: S. Collaud Basset
Author: G. Herrero-Beaumont
Author: A. Migliore
Author: K. Pavelka
Author: D. Uebelhart
Author: J.Y. Reginster

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×