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Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice

Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice
Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice
This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other pharmacological modalities used in this indication. Effectiveness of intra-articular hyaluronic acid has also been highlighted based on ‘real-life' data, together with the clinical benefit of systematic repeated treatment cycles, and the influence of the molecular weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful to clinicians when making personalized care decisions.
0004-3591
1-37
Cooper, C.
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Rannou, F.
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Richette, P.
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Bruyere, O.
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Al-Daghri, N.
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Altman, R.D.
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Luisa-Brandi, M.
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Collaud Basset, S.
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Herrero-Beaumont, G.
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Migliore, A.
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Pavelka, K.
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Uebelhart, D.
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Reginster, J.Y.
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Cooper, C.
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Rannou, F.
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Richette, P.
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Bruyere, O.
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Al-Daghri, N.
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Altman, R.D.
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Luisa-Brandi, M.
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Collaud Basset, S.
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Herrero-Beaumont, G.
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Migliore, A.
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Pavelka, K.
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Uebelhart, D.
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Reginster, J.Y.
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Cooper, C., Rannou, F., Richette, P., Bruyere, O., Al-Daghri, N., Altman, R.D., Luisa-Brandi, M., Collaud Basset, S., Herrero-Beaumont, G., Migliore, A., Pavelka, K., Uebelhart, D. and Reginster, J.Y. (2017) Use of intra-articular hyaluronic acid in management of knee osteoarthritis in clinical practice. Arthritis & Rheumatism, 1-37. (doi:10.1002/acr.23204). (PMID:28118523)

Record type: Article

Abstract

This review emphasizes the safety profile of intra-articular hyaluronic acid treatment of knee osteoarthritis, as well as its moderate but real efficacy on symptoms, which is in the same range than other pharmacological modalities used in this indication. Effectiveness of intra-articular hyaluronic acid has also been highlighted based on ‘real-life' data, together with the clinical benefit of systematic repeated treatment cycles, and the influence of the molecular weight of hyaluronic acid on treatment outcome. These aspects should be particularly helpful to clinicians when making personalized care decisions.

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Accepted/In Press date: 17 January 2017
e-pub ahead of print date: 24 January 2017
Organisations: MRC Life-Course Epidemiology Unit

Identifiers

Local EPrints ID: 405185
URI: http://eprints.soton.ac.uk/id/eprint/405185
ISSN: 0004-3591
PURE UUID: 0ed59918-1b8c-4caa-9471-d29fcbdfd0fc
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 30 Jan 2017 10:25
Last modified: 09 Jan 2022 06:31

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Contributors

Author: C. Cooper ORCID iD
Author: F. Rannou
Author: P. Richette
Author: O. Bruyere
Author: N. Al-Daghri
Author: R.D. Altman
Author: M. Luisa-Brandi
Author: S. Collaud Basset
Author: G. Herrero-Beaumont
Author: A. Migliore
Author: K. Pavelka
Author: D. Uebelhart
Author: J.Y. Reginster

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