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Phase contrast synchrotron radiation computed tomography of muscle spindles in the mouse soleus muscle

Phase contrast synchrotron radiation computed tomography of muscle spindles in the mouse soleus muscle
Phase contrast synchrotron radiation computed tomography of muscle spindles in the mouse soleus muscle
Muscle spindles are skeletal muscle sensory organs involved in the sensation of position and movement of the body. We have explored the capability of phase contrast computed tomography to visualise muscle spindles in murine skeletal muscle. In particular, we have validated the visualisation of nerve fibres through phase contrast computed tomography using light microscopy on stained histological sections. We further present the first 3D visualisation of muscle spindles in mouse soleus skeletal muscle in conjunction with the neurovascular bundle associated with it.
muscle spindles, neurovascular bundle, phase contrast, synchrotron radiation, computed tomography
0021-8782
859-865
Zeller-Plumhoff, Berit
1a9d6525-3f1f-4a0b-89ba-e5042ceb37f4
Roose, Tiina
3581ab5b-71e1-4897-8d88-59f13f3bccfe
Mavrogordato, Mark
f3e0879b-118a-463a-a130-1c890e9ab547
Katsamenis, Orestis
8553e7c3-d860-4b7a-a883-abf6c0c4b438
Torrens, Christopher
15a35713-0651-4249-8227-5901e2cfcd22
Schneider, Philipp
a810f925-4808-44e4-8a4a-a51586f9d7ad
Clough, Geraldine
9f19639e-a929-4976-ac35-259f9011c494
Zeller-Plumhoff, Berit
1a9d6525-3f1f-4a0b-89ba-e5042ceb37f4
Roose, Tiina
3581ab5b-71e1-4897-8d88-59f13f3bccfe
Mavrogordato, Mark
f3e0879b-118a-463a-a130-1c890e9ab547
Katsamenis, Orestis
8553e7c3-d860-4b7a-a883-abf6c0c4b438
Torrens, Christopher
15a35713-0651-4249-8227-5901e2cfcd22
Schneider, Philipp
a810f925-4808-44e4-8a4a-a51586f9d7ad
Clough, Geraldine
9f19639e-a929-4976-ac35-259f9011c494

Zeller-Plumhoff, Berit, Roose, Tiina, Mavrogordato, Mark, Katsamenis, Orestis, Torrens, Christopher, Schneider, Philipp and Clough, Geraldine (2017) Phase contrast synchrotron radiation computed tomography of muscle spindles in the mouse soleus muscle. Journal of Anatomy, 230 (6), 859-865. (doi:10.1111/joa.12606).

Record type: Article

Abstract

Muscle spindles are skeletal muscle sensory organs involved in the sensation of position and movement of the body. We have explored the capability of phase contrast computed tomography to visualise muscle spindles in murine skeletal muscle. In particular, we have validated the visualisation of nerve fibres through phase contrast computed tomography using light microscopy on stained histological sections. We further present the first 3D visualisation of muscle spindles in mouse soleus skeletal muscle in conjunction with the neurovascular bundle associated with it.

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Accepted/In Press date: 9 February 2017
e-pub ahead of print date: 29 March 2017
Published date: June 2017
Keywords: muscle spindles, neurovascular bundle, phase contrast, synchrotron radiation, computed tomography
Organisations: Engineering Mats & Surface Engineerg Gp, Engineering Science Unit, nCATS Group

Identifiers

Local EPrints ID: 405802
URI: http://eprints.soton.ac.uk/id/eprint/405802
ISSN: 0021-8782
PURE UUID: a69319cd-4571-42c4-a8a9-8064c2239067
ORCID for Tiina Roose: ORCID iD orcid.org/0000-0001-8710-1063
ORCID for Orestis Katsamenis: ORCID iD orcid.org/0000-0003-4367-4147
ORCID for Philipp Schneider: ORCID iD orcid.org/0000-0001-7499-3576
ORCID for Geraldine Clough: ORCID iD orcid.org/0000-0002-6226-8964

Catalogue record

Date deposited: 10 Feb 2017 14:37
Last modified: 16 Mar 2024 04:17

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Contributors

Author: Berit Zeller-Plumhoff
Author: Tiina Roose ORCID iD
Author: Christopher Torrens

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