Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting
Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting
Osteoporosis represents a significant and increasing healthcare burden in Europe, but most patients at increased risk of fracture do not receive medication, resulting in a large treatment gap. Identification of patients who are at particularly high risk will help clinicians target appropriate treatment more precisely and cost-effectively, and should be the focus of future research.
Introduction: The purpose of the study was to review data on the identification and treatment of patients with osteoporosis at increased risk of fracture.
Methods: A working group convened by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis met to review current data on the epidemiology and burden of osteoporosis and the patterns of medical management throughout Europe.
Results: In Europe in 2010, the cost of managing osteoporosis was estimated at €37 billion and notably the costs of treatment and long-term care of patients with fractures were considerably higher than the costs for pharmacological prevention. Despite the availability of effective treatments, the uptake of osteoporosis therapy is low and declining, in particular for secondary fracture prevention where the risk of a subsequent fracture following a first fracture is high. Consequently, there is a significant treatment gap between those who would benefit from treatment and those who receive it, which urgently needs to be addressed so that the burden of disease can be reduced.
Conclusions: Implementation of global fracture prevention strategies is a critical need. Future research should focus on identifying specific risk factors for imminent fractures, periods of high fracture risk, patients who are at increased risk of fracture and therapies that are most suited to such high-risk patients and optimal implementation strategies in primary, secondary and tertiary care.
2023–2034
Kanis, J.A.
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Cooper, Cyrus
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Rizzoli, Rene
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Abrahamsen, Bo
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Al-Daghri, N.M.
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Brandi, M.-L.
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Cannata-Andia, J.
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Cortet, B.
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Dimai, H P
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Ferrari, S
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Hadji, P.
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Harvey, Nicholas
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Kraenzlin, M.
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Kurth, A.
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McCloskey, Eugene
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Minisola, S.
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Thomas, T.
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Reginster, J.-Y.
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7 August 2017
Kanis, J.A.
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Cooper, Cyrus
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Rizzoli, Rene
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Abrahamsen, Bo
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Al-Daghri, N.M.
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Brandi, M.-L.
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Cannata-Andia, J.
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Cortet, B.
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Dimai, H P
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Ferrari, S
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Hadji, P.
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Harvey, Nicholas
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Kraenzlin, M.
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Kurth, A.
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McCloskey, Eugene
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Minisola, S.
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Thomas, T.
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Reginster, J.-Y.
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Kanis, J.A., Cooper, Cyrus, Rizzoli, Rene, Abrahamsen, Bo, Al-Daghri, N.M., Brandi, M.-L., Cannata-Andia, J., Cortet, B., Dimai, H P, Ferrari, S, Hadji, P., Harvey, Nicholas, Kraenzlin, M., Kurth, A., McCloskey, Eugene, Minisola, S., Thomas, T. and Reginster, J.-Y.
(2017)
Identification and management of patients at increased risk of osteoporotic fracture: Outcomes of an ESCEO expert consensus meeting.
Osteoporosis International, 28 (7), .
(doi:10.1007/s00198-017-4161-6).
Abstract
Osteoporosis represents a significant and increasing healthcare burden in Europe, but most patients at increased risk of fracture do not receive medication, resulting in a large treatment gap. Identification of patients who are at particularly high risk will help clinicians target appropriate treatment more precisely and cost-effectively, and should be the focus of future research.
Introduction: The purpose of the study was to review data on the identification and treatment of patients with osteoporosis at increased risk of fracture.
Methods: A working group convened by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis met to review current data on the epidemiology and burden of osteoporosis and the patterns of medical management throughout Europe.
Results: In Europe in 2010, the cost of managing osteoporosis was estimated at €37 billion and notably the costs of treatment and long-term care of patients with fractures were considerably higher than the costs for pharmacological prevention. Despite the availability of effective treatments, the uptake of osteoporosis therapy is low and declining, in particular for secondary fracture prevention where the risk of a subsequent fracture following a first fracture is high. Consequently, there is a significant treatment gap between those who would benefit from treatment and those who receive it, which urgently needs to be addressed so that the burden of disease can be reduced.
Conclusions: Implementation of global fracture prevention strategies is a critical need. Future research should focus on identifying specific risk factors for imminent fractures, periods of high fracture risk, patients who are at increased risk of fracture and therapies that are most suited to such high-risk patients and optimal implementation strategies in primary, secondary and tertiary care.
Text
Increased fracture risk OI revision R1 jk
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More information
Accepted/In Press date: 8 March 2017
Published date: 7 August 2017
Additional Information:
DOI: 10.1007/s00198-017-4009-0
The article “Identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting”, written by J.A. Kanis, C. Cooper, R. Rizzoli, B. Abrahamsen, N. M. Al-Daghri, M. L. Brandi, J. Cannata-Andia, B. Cortet, H. P. Dimai, S. Ferrari, P. Hadji, N. C. Harvey, M. Kraenzlin, A. Kurth, E. McCloskey, S. Minisola17, T. Thomas, and J.-Y. Reginster for the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), was originally published Online First without open access. After publication in volume 28, issue 7, pages 2023–2034 the author decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2017 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and the source, a link to the Creative Commons license is provided, and any changes made are indicated.
Organisations:
Human Development & Health, Medical Research Council
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Local EPrints ID: 407005
URI: http://eprints.soton.ac.uk/id/eprint/407005
ISSN: 0937-941X
PURE UUID: ca033bbc-595c-4b47-bc4b-9689fe22046c
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Date deposited: 29 Mar 2017 01:09
Last modified: 18 Mar 2024 05:03
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Contributors
Author:
J.A. Kanis
Author:
Rene Rizzoli
Author:
Bo Abrahamsen
Author:
N.M. Al-Daghri
Author:
M.-L. Brandi
Author:
J. Cannata-Andia
Author:
B. Cortet
Author:
H P Dimai
Author:
S Ferrari
Author:
P. Hadji
Author:
M. Kraenzlin
Author:
A. Kurth
Author:
Eugene McCloskey
Author:
S. Minisola
Author:
T. Thomas
Author:
J.-Y. Reginster
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