The geography of measles vaccination in the African Great Lakes region
The geography of measles vaccination in the African Great Lakes region
Expanded access to measles vaccination was among the most successful public health interventions of recent decades. All WHO regions currently target measles elimination by 2020, yet continued measles circulation makes that goal seem elusive. Using Demographic and Health Surveys with generalized additive models, we quantify spatial patterns of measles vaccination in ten contiguous countries in the African Great Lakes region between 2009–2014. Seven countries have ‘coldspots’ where vaccine coverage is below the WHO target of 80%. Over 14 million children under 5 years of age live in coldspots across the region, and a total of 8–12 million children are unvaccinated. Spatial patterns of vaccination do not map directly onto sub-national administrative units and transnational coldspots exist. Clustering of low vaccination areas may allow for pockets of susceptibility that sustain circulation despite high overall coverage. Targeting at-risk areas and transnational coordination are likely required to eliminate measles in the region.
measles virus, Policy and public health in microbiology, vaccines, viral epidemiology
Takahashi, Saki
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Metcalf, C. Jessica E.
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Ferrari, Matthew J.
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Tatem, Andrew
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Lessler, Justin
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2017
Takahashi, Saki
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Metcalf, C. Jessica E.
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Ferrari, Matthew J.
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Tatem, Andrew
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Lessler, Justin
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Takahashi, Saki, Metcalf, C. Jessica E., Ferrari, Matthew J., Tatem, Andrew and Lessler, Justin
(2017)
The geography of measles vaccination in the African Great Lakes region.
Nature Communications, 8, [15585].
(doi:10.1038/ncomms15585).
Abstract
Expanded access to measles vaccination was among the most successful public health interventions of recent decades. All WHO regions currently target measles elimination by 2020, yet continued measles circulation makes that goal seem elusive. Using Demographic and Health Surveys with generalized additive models, we quantify spatial patterns of measles vaccination in ten contiguous countries in the African Great Lakes region between 2009–2014. Seven countries have ‘coldspots’ where vaccine coverage is below the WHO target of 80%. Over 14 million children under 5 years of age live in coldspots across the region, and a total of 8–12 million children are unvaccinated. Spatial patterns of vaccination do not map directly onto sub-national administrative units and transnational coldspots exist. Clustering of low vaccination areas may allow for pockets of susceptibility that sustain circulation despite high overall coverage. Targeting at-risk areas and transnational coordination are likely required to eliminate measles in the region.
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MappingColdspots_ToCirculate_mf-ajt
- Accepted Manuscript
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ncomms15585
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More information
Accepted/In Press date: 7 April 2017
e-pub ahead of print date: 25 May 2017
Published date: 2017
Keywords:
measles virus, Policy and public health in microbiology, vaccines, viral epidemiology
Organisations:
WorldPop, Geography & Environment, Population, Health & Wellbeing (PHeW)
Identifiers
Local EPrints ID: 411033
URI: http://eprints.soton.ac.uk/id/eprint/411033
PURE UUID: e3327122-0b47-4416-9ea6-214f05f8ac81
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Date deposited: 13 Jun 2017 16:32
Last modified: 16 Mar 2024 04:11
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Contributors
Author:
Saki Takahashi
Author:
C. Jessica E. Metcalf
Author:
Matthew J. Ferrari
Author:
Justin Lessler
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