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The active template approach to interlocked molecules

The active template approach to interlocked molecules
The active template approach to interlocked molecules
The active template approach to interlocked molecules takes advantage of the ability of metal ions to both organize precursor fragments for mechanical bond formation and to mediate the final covalent bond-forming reaction that captures the interlocked structure. Since its inception just a decade ago, this new methodology has expanded rapidly from a single reaction for rotaxane synthesis to a range of metal-mediated bond formations for the synthesis of complex interlocked molecules. In this Review, we introduce the active template concept, its key advantages for the synthesis of interlocked molecules and outline recent advances that have been made using this technology. We will conclude with comments about future directions and challenges.
2397-3358
Denis, Mathieu
05f9a9b4-df98-4cc8-bebf-33e99bc91e7d
Goldup, Stephen M.
0a93eedd-98bb-42c1-a963-e2815665e937
Denis, Mathieu
05f9a9b4-df98-4cc8-bebf-33e99bc91e7d
Goldup, Stephen M.
0a93eedd-98bb-42c1-a963-e2815665e937

Denis, Mathieu and Goldup, Stephen M. (2017) The active template approach to interlocked molecules. Nature Reviews Chemistry, 1, [0061]. (doi:10.1038/s41570-017-0061).

Record type: Review

Abstract

The active template approach to interlocked molecules takes advantage of the ability of metal ions to both organize precursor fragments for mechanical bond formation and to mediate the final covalent bond-forming reaction that captures the interlocked structure. Since its inception just a decade ago, this new methodology has expanded rapidly from a single reaction for rotaxane synthesis to a range of metal-mediated bond formations for the synthesis of complex interlocked molecules. In this Review, we introduce the active template concept, its key advantages for the synthesis of interlocked molecules and outline recent advances that have been made using this technology. We will conclude with comments about future directions and challenges.

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Accepted/In Press date: 4 July 2017
e-pub ahead of print date: 9 August 2017

Identifiers

Local EPrints ID: 412997
URI: http://eprints.soton.ac.uk/id/eprint/412997
ISSN: 2397-3358
PURE UUID: f26fac25-22a5-4356-b981-471f5751ff71
ORCID for Stephen M. Goldup: ORCID iD orcid.org/0000-0003-3781-0464

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Date deposited: 10 Aug 2017 16:30
Last modified: 07 Oct 2020 04:25

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Author: Mathieu Denis

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