The University of Southampton
University of Southampton Institutional Repository

Overview of fracture prediction tools

Overview of fracture prediction tools
Overview of fracture prediction tools
The characterization of risk factors for fracture that contribute significantly to fracture risk, over and above that provided by the bone mineral density, has stimulated the development of risk assessment tools. The more adequately evaluated tools, all available online, include the FRAX® tool, the Garvan fracture risk calculator and, in the United Kingdom only, QFracture®. Differences in the input variables, output, and model construct give rise to marked differences in the computed risks from each calculator. Reasons for the differences include the derivation of fracture probability (FRAX) rather than incidence (Garvan and QFracture), limited calibration (Garvan), and inappropriate source information (QFracture). These differences need to be taken into account in the evaluation of assessment guidelines.
1094-6950
Kanis, John A.
f1621d8d-8afb-4d97-9679-2165d88a344d
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Johansson, Helena
04f12338-4dd1-437b-b9bc-e0884130c215
Odén, Anders
cc56db15-a8d7-40f3-bd92-59d7a9abbf62
McCloskey, Eugene V.
2f057a16-3d4e-4597-80c7-6ce47f969c78
Leslie, William D.
5b2dd5d6-4569-40a3-a9b1-95152d11e4f1
Kanis, John A.
f1621d8d-8afb-4d97-9679-2165d88a344d
Harvey, Nicholas
ce487fb4-d360-4aac-9d17-9466d6cba145
Johansson, Helena
04f12338-4dd1-437b-b9bc-e0884130c215
Odén, Anders
cc56db15-a8d7-40f3-bd92-59d7a9abbf62
McCloskey, Eugene V.
2f057a16-3d4e-4597-80c7-6ce47f969c78
Leslie, William D.
5b2dd5d6-4569-40a3-a9b1-95152d11e4f1

Kanis, John A., Harvey, Nicholas, Johansson, Helena, Odén, Anders, McCloskey, Eugene V. and Leslie, William D. (2017) Overview of fracture prediction tools. Journal of Clinical Densitometry. (doi:10.1016/j.jocd.2017.06.013).

Record type: Article

Abstract

The characterization of risk factors for fracture that contribute significantly to fracture risk, over and above that provided by the bone mineral density, has stimulated the development of risk assessment tools. The more adequately evaluated tools, all available online, include the FRAX® tool, the Garvan fracture risk calculator and, in the United Kingdom only, QFracture®. Differences in the input variables, output, and model construct give rise to marked differences in the computed risks from each calculator. Reasons for the differences include the derivation of fracture probability (FRAX) rather than incidence (Garvan and QFracture), limited calibration (Garvan), and inappropriate source information (QFracture). These differences need to be taken into account in the evaluation of assessment guidelines.

Text
Ch 18 Comparisons v2 - Accepted Manuscript
Download (128kB)

More information

Accepted/In Press date: 14 July 2017
e-pub ahead of print date: 14 July 2017

Identifiers

Local EPrints ID: 413503
URI: http://eprints.soton.ac.uk/id/eprint/413503
ISSN: 1094-6950
PURE UUID: 576ad93c-7962-44bd-af45-d7d74c7a7b4d
ORCID for Nicholas Harvey: ORCID iD orcid.org/0000-0002-8194-2512

Catalogue record

Date deposited: 25 Aug 2017 16:31
Last modified: 16 Mar 2024 05:41

Export record

Altmetrics

Contributors

Author: John A. Kanis
Author: Nicholas Harvey ORCID iD
Author: Helena Johansson
Author: Anders Odén
Author: Eugene V. McCloskey
Author: William D. Leslie

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×