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Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer

Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer
Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer
Objective:

Identify existing resources developed and/or evaluated empirically in the published literature designed to support women with breast cancer making decisions regarding genetic testing for BRCA1/2 mutations.

Methods:

Systematic review of seven electronic databases. Studies were included if they described or evaluated resources that were designed to support women with breast cancer in making a decision to have genetic counselling or testing for familial breast cancer. Outcome and process evaluations, using any type of study design, as well as articles reporting the development of decision aids, were eligible for inclusion.

Results:

Total of 9 publications, describing 6 resources were identified. Resources were effective at increasing knowledge or understanding of hereditary breast cancer. Satisfaction with resources was high. There was no evidence that any resource increased distress, worry or decisional conflict. Few resources included active functionalities for example, values-based exercises, to support decision-making.

Conclusion:

Tailored resources supporting decision-making may be helpful and valued by patients and increase knowledge of hereditary breast cancer, without causing additional distress.
Practice implications:

Clinicians should provide supportive written information to patients where it is available. However, there is a need for robustly developed decision tools to support decision-making around genetic testing in women with breast cancer.
0738-3991
779-788
Grimmett, Chloe
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Pickett, Karen
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Shepherd, Jonathan
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Welch, Karen
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Recio Saucedo, Alejandra
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Streit, Elke
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Seers, Helen
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Armstrong, Anne
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Cutress, Ramsey I.
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Evans, D. Gareth
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Copson, Ellen
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Meiser, Bettina
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Eccles, Diana
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Foster, Claire
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Grimmett, Chloe
7f27e85b-2850-481d-a7dd-2835e1a925cd
Pickett, Karen
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Shepherd, Jonathan
dfbca97a-9307-4eee-bdf7-e27bcb02bc67
Welch, Karen
2603c214-aace-486f-8723-b006873248a5
Recio Saucedo, Alejandra
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Streit, Elke
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Seers, Helen
abc0b31f-3c1d-43a6-83f4-2efd71606812
Armstrong, Anne
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Cutress, Ramsey I.
68ae4f86-e8cf-411f-a335-cdba51797406
Evans, D. Gareth
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Copson, Ellen
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Meiser, Bettina
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Eccles, Diana
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Foster, Claire
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Grimmett, Chloe, Pickett, Karen, Shepherd, Jonathan, Welch, Karen, Recio Saucedo, Alejandra, Streit, Elke, Seers, Helen, Armstrong, Anne, Cutress, Ramsey I., Evans, D. Gareth, Copson, Ellen, Meiser, Bettina, Eccles, Diana and Foster, Claire (2017) Systematic review of the empirical investigation of resources to support decision-making regarding BRCA1 and BRCA2 genetic testing in women with breast cancer. Patient Education and Counseling, 101, 779-788. (doi:10.1016/j.pec.2017.11.016).

Record type: Article

Abstract

Objective:

Identify existing resources developed and/or evaluated empirically in the published literature designed to support women with breast cancer making decisions regarding genetic testing for BRCA1/2 mutations.

Methods:

Systematic review of seven electronic databases. Studies were included if they described or evaluated resources that were designed to support women with breast cancer in making a decision to have genetic counselling or testing for familial breast cancer. Outcome and process evaluations, using any type of study design, as well as articles reporting the development of decision aids, were eligible for inclusion.

Results:

Total of 9 publications, describing 6 resources were identified. Resources were effective at increasing knowledge or understanding of hereditary breast cancer. Satisfaction with resources was high. There was no evidence that any resource increased distress, worry or decisional conflict. Few resources included active functionalities for example, values-based exercises, to support decision-making.

Conclusion:

Tailored resources supporting decision-making may be helpful and valued by patients and increase knowledge of hereditary breast cancer, without causing additional distress.
Practice implications:

Clinicians should provide supportive written information to patients where it is available. However, there is a need for robustly developed decision tools to support decision-making around genetic testing in women with breast cancer.

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More information

Accepted/In Press date: 24 November 2017
e-pub ahead of print date: 26 November 2017

Identifiers

Local EPrints ID: 416733
URI: http://eprints.soton.ac.uk/id/eprint/416733
ISSN: 0738-3991
PURE UUID: 51717f68-e05d-4df7-a7d5-472245a68bb0
ORCID for Chloe Grimmett: ORCID iD orcid.org/0000-0002-7540-7206
ORCID for Karen Pickett: ORCID iD orcid.org/0000-0002-8631-6465
ORCID for Jonathan Shepherd: ORCID iD orcid.org/0000-0003-1682-4330
ORCID for Alejandra Recio Saucedo: ORCID iD orcid.org/0000-0003-2823-4573
ORCID for Diana Eccles: ORCID iD orcid.org/0000-0002-9935-3169
ORCID for Claire Foster: ORCID iD orcid.org/0000-0002-4703-8378

Catalogue record

Date deposited: 05 Jan 2018 17:30
Last modified: 16 Mar 2024 06:00

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Contributors

Author: Chloe Grimmett ORCID iD
Author: Karen Pickett ORCID iD
Author: Karen Welch
Author: Elke Streit
Author: Helen Seers
Author: Anne Armstrong
Author: D. Gareth Evans
Author: Ellen Copson
Author: Bettina Meiser
Author: Diana Eccles ORCID iD
Author: Claire Foster ORCID iD

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