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Core outcome domains in incontinence‐associated dermatitis research

Core outcome domains in incontinence‐associated dermatitis research
Core outcome domains in incontinence‐associated dermatitis research
Aim

To report the development of a core set of outcome domains for clinical research involving adults with incontinence‐associated dermatitis or at risk, independently from any geographical location or skin colour.

Background

The management of incontinence‐associated dermatitis is important in caring for incontinent patients. The lack of comparability of clinical trial outcomes is a major challenge in the field of evidence‐based incontinence‐associated dermatitis prevention and treatment. Core outcome sets may therefore be helpful to improve the value of clinical incontinence‐associated dermatitis research.

Design

Systematic literature review, patient interviews and consensus study using Delphi procedure.

Methods

A list of outcome domains was generated through a systematic literature review (no date restrictions—April 2016), consultation of an international steering committee and three patient interviews. The project team reviewed and refined the outcome domains prior to starting a three‐round Delphi procedure conducted between April–September 2017. The panellists, including healthcare providers, researchers and industry were invited to rate the importance of the outcome domains.

Results

We extracted 1,852 outcomes from 244 articles. Experts proposed 56 and patients 32 outcome domains. After refinement, 57 panellists from 17 countries rated a list of 58 outcome domains. The final list of outcome domains includes erythema, erosion, maceration, IAD‐related pain and patient satisfaction.

Conclusion

Erythema, erosion, maceration, incontinence‐associated dermatitis ‐related pain and patient satisfaction are the most important outcome domains to be measured in incontinence‐associated dermatitis trials. Based on this international consensus on what to measure, the question of how to measure these domains now requires consideration.
0309-2402
Van Den Bussche, Karen
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Kottner, Jan
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Beele, Hilde
8d09810f-e9b8-4474-8dd2-23b729fd3319
De Meyer, Dorien
e9af95f3-c243-40d7-9cd0-544057c69a2e
Dunk, Ann Marie
d36a16d2-a5cc-41b4-8068-282b0888cad3
Ersser, Steven
09c17777-b01e-495e-b3ad-d7e4035b88e2
Lange, Toni
52ec27c6-1863-405e-be80-7c65d7bd03df
Petrovic, Mirko
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Schoonhoven, Lisette
46a2705b-c657-409b-b9da-329d5b1b02de
Smet, Steven
12b2b9db-9237-488f-9143-d0197a98c391
Van Damme, Nele
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Verhaeghe, Sofie
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Van Hecke, Ann
094eb12d-9032-412f-95ad-43d519aa8933
Beeckman, Dimitri
1ead183b-0e82-4b3f-864b-8dfc2e58de3e
Van Den Bussche, Karen
49e6d4e0-e7bf-4173-b76a-aaf12440a4f9
Kottner, Jan
50d0d629-8765-445b-b21d-11dbc4e6e504
Beele, Hilde
8d09810f-e9b8-4474-8dd2-23b729fd3319
De Meyer, Dorien
e9af95f3-c243-40d7-9cd0-544057c69a2e
Dunk, Ann Marie
d36a16d2-a5cc-41b4-8068-282b0888cad3
Ersser, Steven
09c17777-b01e-495e-b3ad-d7e4035b88e2
Lange, Toni
52ec27c6-1863-405e-be80-7c65d7bd03df
Petrovic, Mirko
7bbd64fb-c748-4447-b4d5-2aa77527ec12
Schoonhoven, Lisette
46a2705b-c657-409b-b9da-329d5b1b02de
Smet, Steven
12b2b9db-9237-488f-9143-d0197a98c391
Van Damme, Nele
bf523362-1ee1-4e90-8b4f-05917345853a
Verhaeghe, Sofie
0813302f-0299-4e53-af27-f12caf1266dd
Van Hecke, Ann
094eb12d-9032-412f-95ad-43d519aa8933
Beeckman, Dimitri
1ead183b-0e82-4b3f-864b-8dfc2e58de3e

Van Den Bussche, Karen, Kottner, Jan, Beele, Hilde, De Meyer, Dorien, Dunk, Ann Marie, Ersser, Steven, Lange, Toni, Petrovic, Mirko, Schoonhoven, Lisette, Smet, Steven, Van Damme, Nele, Verhaeghe, Sofie, Van Hecke, Ann and Beeckman, Dimitri (2018) Core outcome domains in incontinence‐associated dermatitis research. Journal of Advanced Nursing. (doi:10.1111/jan.13562).

Record type: Article

Abstract

Aim

To report the development of a core set of outcome domains for clinical research involving adults with incontinence‐associated dermatitis or at risk, independently from any geographical location or skin colour.

Background

The management of incontinence‐associated dermatitis is important in caring for incontinent patients. The lack of comparability of clinical trial outcomes is a major challenge in the field of evidence‐based incontinence‐associated dermatitis prevention and treatment. Core outcome sets may therefore be helpful to improve the value of clinical incontinence‐associated dermatitis research.

Design

Systematic literature review, patient interviews and consensus study using Delphi procedure.

Methods

A list of outcome domains was generated through a systematic literature review (no date restrictions—April 2016), consultation of an international steering committee and three patient interviews. The project team reviewed and refined the outcome domains prior to starting a three‐round Delphi procedure conducted between April–September 2017. The panellists, including healthcare providers, researchers and industry were invited to rate the importance of the outcome domains.

Results

We extracted 1,852 outcomes from 244 articles. Experts proposed 56 and patients 32 outcome domains. After refinement, 57 panellists from 17 countries rated a list of 58 outcome domains. The final list of outcome domains includes erythema, erosion, maceration, IAD‐related pain and patient satisfaction.

Conclusion

Erythema, erosion, maceration, incontinence‐associated dermatitis ‐related pain and patient satisfaction are the most important outcome domains to be measured in incontinence‐associated dermatitis trials. Based on this international consensus on what to measure, the question of how to measure these domains now requires consideration.

Text
Core Outcome Set in IAD Research (CONSIDER): international and multidisciplinary consensus on a core set of outcome domains in incontinence-associated dermatitis research - Accepted Manuscript
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More information

Accepted/In Press date: 20 February 2018
e-pub ahead of print date: 6 April 2018

Identifiers

Local EPrints ID: 418557
URI: http://eprints.soton.ac.uk/id/eprint/418557
ISSN: 0309-2402
PURE UUID: bcc08590-2a8a-4cae-91b5-4c6fa2b62b42
ORCID for Lisette Schoonhoven: ORCID iD orcid.org/0000-0002-7129-3766

Catalogue record

Date deposited: 12 Mar 2018 17:30
Last modified: 16 Mar 2024 06:18

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Contributors

Author: Karen Van Den Bussche
Author: Jan Kottner
Author: Hilde Beele
Author: Dorien De Meyer
Author: Ann Marie Dunk
Author: Steven Ersser
Author: Toni Lange
Author: Mirko Petrovic
Author: Steven Smet
Author: Nele Van Damme
Author: Sofie Verhaeghe
Author: Ann Van Hecke
Author: Dimitri Beeckman

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