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Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study

Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study
Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study

There are few data describing associations between dietary patterns and bone microarchitecture. This study investigated the relationship between diet quality and HRpQCT and pQCT measures in older adults. Data were available for 184 men and 166 women. Dietary data were collected at baseline (1998–2003) using an administered food frequency questionnaire. A ‘prudent’ diet score (PDS) was identified using principal component analysis and used as an indicator of dietary quality. HRpQCT and pQCT images were acquired at follow-up in 2012, from the non-dominant distal radius and tibia using Scanco XtremeCT and Stratec XCT2000 instrument scanners, respectively. The mean (SD) PDS was − 0.24 (1.23) for men and 0.62 (1.14) for women. In women, a significant positive relationship was found between baseline dietary pattern and total and trabecular area at both the radius and the tibia, measured by HRpQCT. Similar trends were observed with pQCT parameters. Positive associations were observed for tibia total area (38% slice). At the radius, significant positive associations were found for total area (4% slice) and polar strength strain index (33% slice). All relationships remained robust to adjustment. For men, although patterns were similar, there were no significant associations for HRpQCT outcomes. Significant associations were observed for baseline PDS and polar strength strain and total area (66% slice) at the radius, measured by pQCT. Our data suggest that diets high in fruit, vegetables, oily fish and whole grain cereals in early old age are associated with greater bone size but not volumetric bone density or microarchitecture in later life in women.

Bone microarchitecture, Diet quality, HRpQCT, Older adults, pQCT
0171-967X
1-7
Shaw, Sarah
9629b12a-8ee2-4483-a9ca-6efb4eef74c8
Parsons, Camille, Michelle
43244c4b-0e18-4657-816d-9f5710cc7b07
Fuggle, Nicholas
ade389ee-fd15-4b34-9716-3541c2b0e7a9
Edwards, Mark
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Robinson, Sian
ba591c98-4380-456a-be8a-c452f992b69b
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Ward, Kathryn
39bd4db1-c948-4e32-930e-7bec8deb54c7
Shaw, Sarah
9629b12a-8ee2-4483-a9ca-6efb4eef74c8
Parsons, Camille, Michelle
43244c4b-0e18-4657-816d-9f5710cc7b07
Fuggle, Nicholas
ade389ee-fd15-4b34-9716-3541c2b0e7a9
Edwards, Mark
06c1db44-4341-455e-8812-0ab4a1043828
Robinson, Sian
ba591c98-4380-456a-be8a-c452f992b69b
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Ward, Kathryn
39bd4db1-c948-4e32-930e-7bec8deb54c7

Shaw, Sarah, Parsons, Camille, Michelle, Fuggle, Nicholas, Edwards, Mark, Robinson, Sian, Dennison, Elaine, Cooper, Cyrus and Ward, Kathryn (2018) Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study. Calcified Tissue International, 1-7. (doi:10.1007/s00223-018-0445-x).

Record type: Article

Abstract

There are few data describing associations between dietary patterns and bone microarchitecture. This study investigated the relationship between diet quality and HRpQCT and pQCT measures in older adults. Data were available for 184 men and 166 women. Dietary data were collected at baseline (1998–2003) using an administered food frequency questionnaire. A ‘prudent’ diet score (PDS) was identified using principal component analysis and used as an indicator of dietary quality. HRpQCT and pQCT images were acquired at follow-up in 2012, from the non-dominant distal radius and tibia using Scanco XtremeCT and Stratec XCT2000 instrument scanners, respectively. The mean (SD) PDS was − 0.24 (1.23) for men and 0.62 (1.14) for women. In women, a significant positive relationship was found between baseline dietary pattern and total and trabecular area at both the radius and the tibia, measured by HRpQCT. Similar trends were observed with pQCT parameters. Positive associations were observed for tibia total area (38% slice). At the radius, significant positive associations were found for total area (4% slice) and polar strength strain index (33% slice). All relationships remained robust to adjustment. For men, although patterns were similar, there were no significant associations for HRpQCT outcomes. Significant associations were observed for baseline PDS and polar strength strain and total area (66% slice) at the radius, measured by pQCT. Our data suggest that diets high in fruit, vegetables, oily fish and whole grain cereals in early old age are associated with greater bone size but not volumetric bone density or microarchitecture in later life in women.

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Accepted/In Press date: 14 June 2018
e-pub ahead of print date: 21 June 2018
Keywords: Bone microarchitecture, Diet quality, HRpQCT, Older adults, pQCT

Identifiers

Local EPrints ID: 421885
URI: https://eprints.soton.ac.uk/id/eprint/421885
ISSN: 0171-967X
PURE UUID: caa03cda-80e9-43e8-9f12-58cf7a9fbab4
ORCID for Sian Robinson: ORCID iD orcid.org/0000-0003-1766-7269
ORCID for Elaine Dennison: ORCID iD orcid.org/0000-0002-3048-4961
ORCID for Cyrus Cooper: ORCID iD orcid.org/0000-0003-3510-0709
ORCID for Kathryn Ward: ORCID iD orcid.org/0000-0001-7034-6750

Catalogue record

Date deposited: 05 Jul 2018 16:30
Last modified: 26 Nov 2019 05:20

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Contributors

Author: Sarah Shaw
Author: Camille, Michelle Parsons
Author: Nicholas Fuggle
Author: Mark Edwards
Author: Sian Robinson ORCID iD
Author: Elaine Dennison ORCID iD
Author: Cyrus Cooper ORCID iD
Author: Kathryn Ward ORCID iD

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