Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study
Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study
There are few data describing associations between dietary patterns and bone microarchitecture. This study investigated the relationship between diet quality and HRpQCT and pQCT measures in older adults. Data were available for 184 men and 166 women. Dietary data were collected at baseline (1998–2003) using an administered food frequency questionnaire. A ‘prudent’ diet score (PDS) was identified using principal component analysis and used as an indicator of dietary quality. HRpQCT and pQCT images were acquired at follow-up in 2012, from the non-dominant distal radius and tibia using Scanco XtremeCT and Stratec XCT2000 instrument scanners, respectively. The mean (SD) PDS was − 0.24 (1.23) for men and 0.62 (1.14) for women. In women, a significant positive relationship was found between baseline dietary pattern and total and trabecular area at both the radius and the tibia, measured by HRpQCT. Similar trends were observed with pQCT parameters. Positive associations were observed for tibia total area (38% slice). At the radius, significant positive associations were found for total area (4% slice) and polar strength strain index (33% slice). All relationships remained robust to adjustment. For men, although patterns were similar, there were no significant associations for HRpQCT outcomes. Significant associations were observed for baseline PDS and polar strength strain and total area (66% slice) at the radius, measured by pQCT. Our data suggest that diets high in fruit, vegetables, oily fish and whole grain cereals in early old age are associated with greater bone size but not volumetric bone density or microarchitecture in later life in women.
Bone microarchitecture, Diet quality, HRpQCT, Older adults, pQCT
1-7
Shaw, Sarah
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Parsons, Camille, Michelle
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Fuggle, Nicholas
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Edwards, Mark
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Robinson, Sian
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Dennison, Elaine
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Cooper, Cyrus
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Ward, Kathryn
39bd4db1-c948-4e32-930e-7bec8deb54c7
Shaw, Sarah
9629b12a-8ee2-4483-a9ca-6efb4eef74c8
Parsons, Camille, Michelle
43244c4b-0e18-4657-816d-9f5710cc7b07
Fuggle, Nicholas
ade389ee-fd15-4b34-9716-3541c2b0e7a9
Edwards, Mark
06c1db44-4341-455e-8812-0ab4a1043828
Robinson, Sian
ba591c98-4380-456a-be8a-c452f992b69b
Dennison, Elaine
ee647287-edb4-4392-8361-e59fd505b1d1
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Ward, Kathryn
39bd4db1-c948-4e32-930e-7bec8deb54c7
Shaw, Sarah, Parsons, Camille, Michelle, Fuggle, Nicholas, Edwards, Mark, Robinson, Sian, Dennison, Elaine, Cooper, Cyrus and Ward, Kathryn
(2018)
Diet quality and bone measurements using HRPQCT and PQCT in older community-dwelling adults from the Hertfordshire Cohort Study.
Calcified Tissue International, .
(doi:10.1007/s00223-018-0445-x).
Abstract
There are few data describing associations between dietary patterns and bone microarchitecture. This study investigated the relationship between diet quality and HRpQCT and pQCT measures in older adults. Data were available for 184 men and 166 women. Dietary data were collected at baseline (1998–2003) using an administered food frequency questionnaire. A ‘prudent’ diet score (PDS) was identified using principal component analysis and used as an indicator of dietary quality. HRpQCT and pQCT images were acquired at follow-up in 2012, from the non-dominant distal radius and tibia using Scanco XtremeCT and Stratec XCT2000 instrument scanners, respectively. The mean (SD) PDS was − 0.24 (1.23) for men and 0.62 (1.14) for women. In women, a significant positive relationship was found between baseline dietary pattern and total and trabecular area at both the radius and the tibia, measured by HRpQCT. Similar trends were observed with pQCT parameters. Positive associations were observed for tibia total area (38% slice). At the radius, significant positive associations were found for total area (4% slice) and polar strength strain index (33% slice). All relationships remained robust to adjustment. For men, although patterns were similar, there were no significant associations for HRpQCT outcomes. Significant associations were observed for baseline PDS and polar strength strain and total area (66% slice) at the radius, measured by pQCT. Our data suggest that diets high in fruit, vegetables, oily fish and whole grain cereals in early old age are associated with greater bone size but not volumetric bone density or microarchitecture in later life in women.
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CLEAN DIET QUALITY AND HRPQCT Manuscript FINAL 130618 after reviewer comments
- Accepted Manuscript
Text
Shaw2018_Article_DietQualityAndBoneMeasurements
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Accepted/In Press date: 14 June 2018
e-pub ahead of print date: 21 June 2018
Keywords:
Bone microarchitecture, Diet quality, HRpQCT, Older adults, pQCT
Identifiers
Local EPrints ID: 421885
URI: http://eprints.soton.ac.uk/id/eprint/421885
ISSN: 0171-967X
PURE UUID: caa03cda-80e9-43e8-9f12-58cf7a9fbab4
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Date deposited: 05 Jul 2018 16:30
Last modified: 18 Mar 2024 05:11
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Author:
Camille, Michelle Parsons
Author:
Nicholas Fuggle
Author:
Mark Edwards
Author:
Sian Robinson
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