Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life
Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life
There is increasing evidence to support the Developmental Origins of Health and Disease (DOHaD) concept that fetal life and early life exposures are important determinants of fetal immune regulation and the development of disorders in later life, including allergies. Among the early life exposures, maternal vitamin D [25(OH)D] status during pregnancy, in particular 25(OH)D insufficiency (25(OH)D concentration of 50‐75nmol/l) and/or 25(OH)D deficiency (25(OH)D concentration <50nmol/l) has been associated with allergic outcomes such as eczema, asthma and rhinitis in their offspring.
117-122
Loo, Evelyn
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Tham, Elizabeth Huiwen
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Pang, Kee Wei
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Goh, Anne
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Teoh, Oon Hoe
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Chong, Yap-Seng
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Gluckman, Peter D.
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Godfrey, Keith
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van Bever, Hugo
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Lee, Bee Wah
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Chong, Mary Foong-Fong
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Shek, Lynette Pei-Chi
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February 2019
Loo, Evelyn
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Tham, Elizabeth Huiwen
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Pang, Kee Wei
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Goh, Anne
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Teoh, Oon Hoe
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Chong, Yap-Seng
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Gluckman, Peter D.
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Godfrey, Keith
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van Bever, Hugo
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Lee, Bee Wah
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Chong, Mary Foong-Fong
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Shek, Lynette Pei-Chi
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Loo, Evelyn, Tham, Elizabeth Huiwen, Pang, Kee Wei, Goh, Anne, Teoh, Oon Hoe, Chong, Yap-Seng, Gluckman, Peter D., Godfrey, Keith, van Bever, Hugo, Lee, Bee Wah, Chong, Mary Foong-Fong and Shek, Lynette Pei-Chi
(2019)
Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life.
Pediatric Allergy and Immunology, 30 (1), .
(doi:10.1111/pai.12995).
Abstract
There is increasing evidence to support the Developmental Origins of Health and Disease (DOHaD) concept that fetal life and early life exposures are important determinants of fetal immune regulation and the development of disorders in later life, including allergies. Among the early life exposures, maternal vitamin D [25(OH)D] status during pregnancy, in particular 25(OH)D insufficiency (25(OH)D concentration of 50‐75nmol/l) and/or 25(OH)D deficiency (25(OH)D concentration <50nmol/l) has been associated with allergic outcomes such as eczema, asthma and rhinitis in their offspring.
Text
Associations btw maternal vit D and allergic outcomes clean EL submitted oct 18
- Accepted Manuscript
More information
Accepted/In Press date: 27 September 2018
e-pub ahead of print date: 19 October 2018
Published date: February 2019
Identifiers
Local EPrints ID: 425579
URI: http://eprints.soton.ac.uk/id/eprint/425579
ISSN: 0905-6157
PURE UUID: 61437752-e37a-47c8-864e-6d37945ca801
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Date deposited: 25 Oct 2018 16:30
Last modified: 16 Mar 2024 07:12
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Contributors
Author:
Evelyn Loo
Author:
Elizabeth Huiwen Tham
Author:
Kee Wei Pang
Author:
Anne Goh
Author:
Oon Hoe Teoh
Author:
Yap-Seng Chong
Author:
Peter D. Gluckman
Author:
Hugo van Bever
Author:
Bee Wah Lee
Author:
Mary Foong-Fong Chong
Author:
Lynette Pei-Chi Shek
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