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Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life

Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life
Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life
There is increasing evidence to support the Developmental Origins of Health and Disease (DOHaD) concept that fetal life and early life exposures are important determinants of fetal immune regulation and the development of disorders in later life, including allergies. Among the early life exposures, maternal vitamin D [25(OH)D] status during pregnancy, in particular 25(OH)D insufficiency (25(OH)D concentration of 50‐75nmol/l) and/or 25(OH)D deficiency (25(OH)D concentration <50nmol/l) has been associated with allergic outcomes such as eczema, asthma and rhinitis in their offspring.
0905-6157
117-122
Loo, Evelyn
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Tham, Elizabeth Huiwen
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Pang, Kee Wei
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Goh, Anne
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Teoh, Oon Hoe
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Chong, Yap-Seng
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Gluckman, Peter D.
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Godfrey, Keith
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van Bever, Hugo
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Lee, Bee Wah
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Chong, Mary Foong-Fong
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Shek, Lynette Pei-Chi
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Loo, Evelyn
4c03cbc8-eed6-4919-b131-aab9bf4c8233
Tham, Elizabeth Huiwen
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Pang, Kee Wei
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Goh, Anne
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Teoh, Oon Hoe
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Chong, Yap-Seng
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Gluckman, Peter D.
e916630e-5ae2-437c-a1d1-8e24c0e05589
Godfrey, Keith
0931701e-fe2c-44b5-8f0d-ec5c7477a6fd
van Bever, Hugo
967ee912-3ad6-4c7b-ab6c-bb50914ea687
Lee, Bee Wah
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Chong, Mary Foong-Fong
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Shek, Lynette Pei-Chi
ff5b44bf-5ab5-4249-8cf1-21751a4f6ae8

Loo, Evelyn, Tham, Elizabeth Huiwen, Pang, Kee Wei, Goh, Anne, Teoh, Oon Hoe, Chong, Yap-Seng, Gluckman, Peter D., Godfrey, Keith, van Bever, Hugo, Lee, Bee Wah, Chong, Mary Foong-Fong and Shek, Lynette Pei-Chi (2019) Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life. Pediatric Allergy and Immunology, 30 (1), 117-122. (doi:10.1111/pai.12995).

Record type: Article

Abstract

There is increasing evidence to support the Developmental Origins of Health and Disease (DOHaD) concept that fetal life and early life exposures are important determinants of fetal immune regulation and the development of disorders in later life, including allergies. Among the early life exposures, maternal vitamin D [25(OH)D] status during pregnancy, in particular 25(OH)D insufficiency (25(OH)D concentration of 50‐75nmol/l) and/or 25(OH)D deficiency (25(OH)D concentration <50nmol/l) has been associated with allergic outcomes such as eczema, asthma and rhinitis in their offspring.

Text
Associations btw maternal vit D and allergic outcomes clean EL submitted oct 18 - Accepted Manuscript
Restricted to Repository staff only until 10 October 2019.
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More information

Accepted/In Press date: 27 September 2018
e-pub ahead of print date: 19 October 2018
Published date: February 2019

Identifiers

Local EPrints ID: 425579
URI: https://eprints.soton.ac.uk/id/eprint/425579
ISSN: 0905-6157
PURE UUID: 61437752-e37a-47c8-864e-6d37945ca801
ORCID for Keith Godfrey: ORCID iD orcid.org/0000-0002-4643-0618

Catalogue record

Date deposited: 25 Oct 2018 16:30
Last modified: 15 Aug 2019 00:56

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