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A novel scoring system for term-equivalent-age cranial ultrasound in extremely preterm infants

A novel scoring system for term-equivalent-age cranial ultrasound in extremely preterm infants
A novel scoring system for term-equivalent-age cranial ultrasound in extremely preterm infants
The role of term-equivalent-age (TEA) cranial ultrasound (cUS) in predicting outcome in preterm infants is increasingly being recognized. However, a detailed quantitative scoring system that allows comparison of groups and comparison with TEA magnetic resonance imaging (MRI) scoring systems is lacking. Eighty-four extremely preterm infants underwent cUS and MRI at TEA. Cranial US was evaluated using a novel detailed scoring system. Agreement between cUS and MRI scores was good (Spearman's ρ = 0.51, p < 0.001). Outcome at 30 mo corrected was assessed in 66 of 84 preterm and 85 term-born infants. Sensitivity was the same for cUS and MRI in prediction of cerebral palsy (75%) and severe cognitive delay (100%); the specificity was slightly higher for MRI (cerebral palsy: 97% vs. 90%, severe cognitive delay: 95% vs. 90%). The proposed novel cUS scoring system is a helpful tool in quantitative assessment of cUS at TEA and prediction of outcome at 30 mo.
0301-5629
786-794
Skiöld, Béatrice
e0462ec7-9993-47b5-92bb-3db4edf06d2d
Hallberg, Boubou
afac0039-8dc9-45c5-a695-4778134abfb1
Vollmer, Brigitte
044f8b55-ba36-4fb2-8e7e-756ab77653ba
Ådén, Ulrika
4d84a0ab-ef6d-4cdc-9653-913f1c4f79f3
Blennow, Mats
14d9f9ca-4587-4372-b964-463355551e31
Horsch, Sandra
7d161f85-dc40-4ab9-bd18-bb8903600e5b
Skiöld, Béatrice
e0462ec7-9993-47b5-92bb-3db4edf06d2d
Hallberg, Boubou
afac0039-8dc9-45c5-a695-4778134abfb1
Vollmer, Brigitte
044f8b55-ba36-4fb2-8e7e-756ab77653ba
Ådén, Ulrika
4d84a0ab-ef6d-4cdc-9653-913f1c4f79f3
Blennow, Mats
14d9f9ca-4587-4372-b964-463355551e31
Horsch, Sandra
7d161f85-dc40-4ab9-bd18-bb8903600e5b

Skiöld, Béatrice, Hallberg, Boubou, Vollmer, Brigitte, Ådén, Ulrika, Blennow, Mats and Horsch, Sandra (2019) A novel scoring system for term-equivalent-age cranial ultrasound in extremely preterm infants. Ultrasound in Medicine & Biology, 45 (3), 786-794. (doi:10.1016/j.ultrasmedbio.2018.11.005).

Record type: Article

Abstract

The role of term-equivalent-age (TEA) cranial ultrasound (cUS) in predicting outcome in preterm infants is increasingly being recognized. However, a detailed quantitative scoring system that allows comparison of groups and comparison with TEA magnetic resonance imaging (MRI) scoring systems is lacking. Eighty-four extremely preterm infants underwent cUS and MRI at TEA. Cranial US was evaluated using a novel detailed scoring system. Agreement between cUS and MRI scores was good (Spearman's ρ = 0.51, p < 0.001). Outcome at 30 mo corrected was assessed in 66 of 84 preterm and 85 term-born infants. Sensitivity was the same for cUS and MRI in prediction of cerebral palsy (75%) and severe cognitive delay (100%); the specificity was slightly higher for MRI (cerebral palsy: 97% vs. 90%, severe cognitive delay: 95% vs. 90%). The proposed novel cUS scoring system is a helpful tool in quantitative assessment of cUS at TEA and prediction of outcome at 30 mo.

Text
Skiöld et al 2018.04.16 cUS scoring at TEA_ Ms_BV - Accepted Manuscript
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More information

Accepted/In Press date: 8 November 2018
e-pub ahead of print date: 2 January 2019
Published date: March 2019

Identifiers

Local EPrints ID: 428924
URI: http://eprints.soton.ac.uk/id/eprint/428924
ISSN: 0301-5629
PURE UUID: 4343bed1-4713-404b-a8eb-abcb85770591
ORCID for Brigitte Vollmer: ORCID iD orcid.org/0000-0003-4088-5336

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Date deposited: 14 Mar 2019 17:30
Last modified: 16 Mar 2024 07:40

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Contributors

Author: Béatrice Skiöld
Author: Boubou Hallberg
Author: Ulrika Ådén
Author: Mats Blennow
Author: Sandra Horsch

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