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Contemporary Concise Review 2018: interstitial lung disease

Contemporary Concise Review 2018: interstitial lung disease
Contemporary Concise Review 2018: interstitial lung disease
The term ‘interstitial lung diseases’ (ILD) refers to heterogeneous disorders with a remarkably different clinical history or prognoses. We use it to clinically define this complex and large group of diseases that share some common characteristics such as the interstitium targeting, the possibility of lung scarring or the radio- logical/histopathological pattern. In contrast with obstructive diseases or lung neoplasms, ILD are quite rare and somewhat challenging due to their unknown cause. However, there is no other field in respiratory medicine that evolved so significantly as ILD during the last 10 years, in particular the idiopathic pulmonary fibrosis (IPF). The personalized medicine is just starting to be the preferred approach for ILD management, and the scientific research is focusing on early disease bio- markers, genomic characterization, real-life treatment’s data and new potential targets in phase I/II trials. With respect to all of these challenging points, this Concise Review aims at showing the recent 2018 updates in ILD with a special focus on those disorders that can be con- sidered to be ‘hot topics’ in the miscellaneous world of ILD such as IPF, sarcoidosis, connective tissue disease associated with ILD (CTD-ILD) and hypersensitivity pneumonitis (HP).
1323-7799
Mari, Pier-Valerio
7542ee2d-d764-43f8-9fd9-2bc2261d3fe5
Jones, Mark
a6fd492e-058e-4e84-a486-34c6035429c1
Richeldi, Luca
540f0654-88a1-4ce1-8141-fb1b1ec1071d
Mari, Pier-Valerio
7542ee2d-d764-43f8-9fd9-2bc2261d3fe5
Jones, Mark
a6fd492e-058e-4e84-a486-34c6035429c1
Richeldi, Luca
540f0654-88a1-4ce1-8141-fb1b1ec1071d

Mari, Pier-Valerio, Jones, Mark and Richeldi, Luca (2019) Contemporary Concise Review 2018: interstitial lung disease. Respirology. (doi:10.1111/resp.13572).

Record type: Review

Abstract

The term ‘interstitial lung diseases’ (ILD) refers to heterogeneous disorders with a remarkably different clinical history or prognoses. We use it to clinically define this complex and large group of diseases that share some common characteristics such as the interstitium targeting, the possibility of lung scarring or the radio- logical/histopathological pattern. In contrast with obstructive diseases or lung neoplasms, ILD are quite rare and somewhat challenging due to their unknown cause. However, there is no other field in respiratory medicine that evolved so significantly as ILD during the last 10 years, in particular the idiopathic pulmonary fibrosis (IPF). The personalized medicine is just starting to be the preferred approach for ILD management, and the scientific research is focusing on early disease bio- markers, genomic characterization, real-life treatment’s data and new potential targets in phase I/II trials. With respect to all of these challenging points, this Concise Review aims at showing the recent 2018 updates in ILD with a special focus on those disorders that can be con- sidered to be ‘hot topics’ in the miscellaneous world of ILD such as IPF, sarcoidosis, connective tissue disease associated with ILD (CTD-ILD) and hypersensitivity pneumonitis (HP).

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Respirology 2019 - Accepted Manuscript
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Accepted/In Press date: 9 April 2019
e-pub ahead of print date: 8 May 2019

Identifiers

Local EPrints ID: 430944
URI: http://eprints.soton.ac.uk/id/eprint/430944
ISSN: 1323-7799
PURE UUID: 39971720-29e7-4921-ad0d-f5da7b70399e
ORCID for Mark Jones: ORCID iD orcid.org/0000-0001-6308-6014

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Date deposited: 17 May 2019 16:30
Last modified: 16 Mar 2024 07:50

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Contributors

Author: Pier-Valerio Mari
Author: Mark Jones ORCID iD
Author: Luca Richeldi

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