Pollen exposure weakens innate defense against respiratory viruses

Accepted/In Press date: 24 June 2019

e-pub ahead of print date: 11 September 2019

Published date: 1 March 2020

Additional Information: Funding Information: This research was partly implemented in the framework of the EUCOST Action DiMoPEx (Diagnosis, Monitoring and Prevention of Exposure‐Related Noncommunicable Diseases), under Grant Number CA15129 (EU Framework Program Horizon 2020). The chair of environmental medicine and SIAF received funding by the Christine‐Kühne‐Center for Allergy Research and Education (CK‐Care). MW received a travel scholarship from the Bayerische Forschungsstiftung (BFS) for her work on the RSV mouse model at Utrecht University. Work including HRV (CB and DED) was funded by the Medical Research Council (UK; G0900453) Helmholtz Association, Germany: Impuls‐ und Vernetzungsfonds (IVF). 1 1 Funding Information: Dr Akdis reports grants from Allergopharma, grants from Idorsia, grants from Swiss National Science Foundation, grants from Christine Kühne‐Center for Allergy Research and Education, grants from European Commission's Horison's 2020 Framework Programme, Cure, other from Sanofi‐Aventis_Regeneron, grants from Novartis Research Institutes, grants from Astra Zeneca, grants from Scibase, outside the submitted work. Dr Chaker reports research grants and other from Allergopharma, ALK Abello, ASIT Biotech, Bencard/Allergen Therapeutics, GSK, HAL Allergy, LETI, LOFARMA, Novartis, Phadia/ Thermo Fisher, Zeller, Circassia; further EIT (European Institute of Technology) and DZL: Deutsches Zentrum Lungenforschung (BMBF, governmental), outside the submitted work. Dr Davies reports personal fees from Synairgen, outside the submitted work; In addition, Dr Davies has a patent with royalties paid. Dr Garssen reports and Two (2) affiliations: (1) Danone/Nutricia Research. Function: Director Research & Innovation Immunology and (2) Utrecht University/Utrecht Institute for Pharmaceutical Sciences. Function: Head Division Pharmacology. The remaining authors declare that they have no conflicts of interest. Publisher Copyright: © 2020 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Keywords: Pollen, antiviral response, lambda interferones, nasal symptoms, non-allergenic pollen compounds, respiratory syncytial virus, rhinovirus;

Local EPrints ID: 432889

URI: http://eprints.soton.ac.uk/id/eprint/432889

DOI: doi:10.1111/all.14047

ISSN: 0105-4538

PURE UUID: 3308efe2-be06-474e-aa87-68ac72306fe8

ORCID for Cornelia Blume: orcid.org/0000-0001-6133-7318

ORCID for Donna E. Davies: orcid.org/0000-0002-5117-2991

Date deposited: 31 Jul 2019 16:30

Last modified: 17 Mar 2024 02:33