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Cytotoxicity and corrosion behavior of magnesium and magnesium alloys in Hank's Solution after processing by high-pressure torsion

Cytotoxicity and corrosion behavior of magnesium and magnesium alloys in Hank's Solution after processing by high-pressure torsion
Cytotoxicity and corrosion behavior of magnesium and magnesium alloys in Hank's Solution after processing by high-pressure torsion

It is well-known that processing by severe plastic deformation using high-pressure torsion (HPT) promotes grain refinement and increases the strength of magnesium and its alloys. The present research is conducted to evaluate the effect of such processing on cytotoxicity and corrosion behavior in Hank's solution by using samples of commercial purity magnesium and AZ31, AZ91, and ZK60 magnesium alloys. All samples are subjected to electrochemical testing and hydrogen evolution testing before and after processing by HPT and the results show that this processing improves the corrosion resistance of pure magnesium, has no significant effect on the AZ31 and AZ91 alloys but reduces the corrosion resistance of the ZK60 alloy. The observations support the conclusion that grain refinement improves the corrosion resistance of metals with a tendency for passivation but impedes the resistance of metals without passivation. In addition, in vitro cytotoxicity tests are performed on the processed materials and show cell viability in all samples. The results demonstrate that HPT processing may be used to improve the performance of magnesium and its alloys as biodegradable implants.

corrosion, cytotoxicity, high-pressure torsion, magnesium, severe plastic deformation
1438-1656
1-9
Lopes, Debora R.
e5337680-cbf4-4bd8-b117-97e327bcc0eb
Silva, Claudio L.P.
83391ea7-c3ae-4729-af7f-62fa94541934
Soares, Renata B.
deabafe8-36af-47ce-8b8f-14e4555f20df
Pereira, Pedro Henrique R.
f033a8a6-ddad-4f6a-91ec-521a3358e4c2
Oliveira, Ana Celeste
f981567b-e6c5-4e3b-8114-4b11db9c80c3
Figueiredo, Roberto B.
184313b8-9f00-451a-bfb1-6d80a2c89b78
Langdon, Terence G.
86e69b4f-e16d-4830-bf8a-5a9c11f0de86
Lins, Vanessa F.C.
6cc9cd28-501a-495d-a452-5ed5366b0601
Lopes, Debora R.
e5337680-cbf4-4bd8-b117-97e327bcc0eb
Silva, Claudio L.P.
83391ea7-c3ae-4729-af7f-62fa94541934
Soares, Renata B.
deabafe8-36af-47ce-8b8f-14e4555f20df
Pereira, Pedro Henrique R.
f033a8a6-ddad-4f6a-91ec-521a3358e4c2
Oliveira, Ana Celeste
f981567b-e6c5-4e3b-8114-4b11db9c80c3
Figueiredo, Roberto B.
184313b8-9f00-451a-bfb1-6d80a2c89b78
Langdon, Terence G.
86e69b4f-e16d-4830-bf8a-5a9c11f0de86
Lins, Vanessa F.C.
6cc9cd28-501a-495d-a452-5ed5366b0601

Lopes, Debora R., Silva, Claudio L.P., Soares, Renata B., Pereira, Pedro Henrique R., Oliveira, Ana Celeste, Figueiredo, Roberto B., Langdon, Terence G. and Lins, Vanessa F.C. (2019) Cytotoxicity and corrosion behavior of magnesium and magnesium alloys in Hank's Solution after processing by high-pressure torsion. Advanced Engineering Materials, 21 (8), 1-9, [1900391]. (doi:10.1002/adem.201900391).

Record type: Article

Abstract

It is well-known that processing by severe plastic deformation using high-pressure torsion (HPT) promotes grain refinement and increases the strength of magnesium and its alloys. The present research is conducted to evaluate the effect of such processing on cytotoxicity and corrosion behavior in Hank's solution by using samples of commercial purity magnesium and AZ31, AZ91, and ZK60 magnesium alloys. All samples are subjected to electrochemical testing and hydrogen evolution testing before and after processing by HPT and the results show that this processing improves the corrosion resistance of pure magnesium, has no significant effect on the AZ31 and AZ91 alloys but reduces the corrosion resistance of the ZK60 alloy. The observations support the conclusion that grain refinement improves the corrosion resistance of metals with a tendency for passivation but impedes the resistance of metals without passivation. In addition, in vitro cytotoxicity tests are performed on the processed materials and show cell viability in all samples. The results demonstrate that HPT processing may be used to improve the performance of magnesium and its alloys as biodegradable implants.

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Lopes 2018 Manuscript - Accepted Manuscript
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Lopes 2018 Figures - Accepted Manuscript
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More information

Accepted/In Press date: 4 July 2019
e-pub ahead of print date: 4 July 2019
Published date: August 2019
Keywords: corrosion, cytotoxicity, high-pressure torsion, magnesium, severe plastic deformation

Identifiers

Local EPrints ID: 433075
URI: http://eprints.soton.ac.uk/id/eprint/433075
ISSN: 1438-1656
PURE UUID: d90b5ff1-1104-44eb-95f8-e33379ed378d
ORCID for Terence G. Langdon: ORCID iD orcid.org/0000-0003-3541-9250

Catalogue record

Date deposited: 07 Aug 2019 16:30
Last modified: 07 Oct 2020 06:44

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