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Latest advancements in ureteral stent technology

Latest advancements in ureteral stent technology
Latest advancements in ureteral stent technology
Urological diseases such as tumours, kidney stones, or strictures in the ureter can lead to a number of health consequences, including life-threatening complications. Ureteral stents have been widely used as a valid solution to restore compromised urological function. Despite their clinical success, stents are subject to failure due to encrustation and biofilm formation, potentially leading to urinary tract infection. The current review focuses on recent advancements in ureteral stent technology, which have been reported in recent scientific journals or patents. Web of Science and Google Scholar have been used as a search engine to perform this review, using the keywords including but not limited to “Ureteral + Stent + Design”, “Ureteral + Stent + Material + Coating”, “Ureteric + Stent” and “Ureteral + Stent”. A significant proportion of technological developments has focused on innovating the stent design to overcome migration and urinary reflux, as well as investigating novel materials and coatings to prevent biofilm formation, such as poly(N,Ndimethylacrylamide) (PDMMA) and swellable polyethylene glycol diacrylate (PEGDA). Biodegradable ureteral stents (BUS) have also emerged as a new generation of endourological devices, overcoming the “forgotten stent syndrome” and reducing healthcare costs. Moreover, efforts have been made to develop pre-clinical test methods, both experimental and computational, which could be employed as a screening platform to inform the design of novel stent technologies.
2223-4691
1-6
De Grazia, Antonio
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Somani, Bhaskar
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Soria, Federico
651dc1a1-8193-4092-a3e5-fa384070fc9b
Carugo, Dario
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Mosayyebi, Ali
ab9cf6da-58c4-4441-993b-7d03d5d3549a
De Grazia, Antonio
cb3a7bf4-094b-4206-812e-b5537760f1e8
Somani, Bhaskar
ab5fd1ce-02df-4b88-b25e-8ece396335d9
Soria, Federico
651dc1a1-8193-4092-a3e5-fa384070fc9b
Carugo, Dario
0a4be6cd-e309-4ed8-a620-20256ce01179
Mosayyebi, Ali
ab9cf6da-58c4-4441-993b-7d03d5d3549a

De Grazia, Antonio, Somani, Bhaskar, Soria, Federico, Carugo, Dario and Mosayyebi, Ali (2019) Latest advancements in ureteral stent technology. Translational Andrology and Urology, 8 (Supplement 4), 1-6. (doi:10.21037/tau.2019.08.16).

Record type: Article

Abstract

Urological diseases such as tumours, kidney stones, or strictures in the ureter can lead to a number of health consequences, including life-threatening complications. Ureteral stents have been widely used as a valid solution to restore compromised urological function. Despite their clinical success, stents are subject to failure due to encrustation and biofilm formation, potentially leading to urinary tract infection. The current review focuses on recent advancements in ureteral stent technology, which have been reported in recent scientific journals or patents. Web of Science and Google Scholar have been used as a search engine to perform this review, using the keywords including but not limited to “Ureteral + Stent + Design”, “Ureteral + Stent + Material + Coating”, “Ureteric + Stent” and “Ureteral + Stent”. A significant proportion of technological developments has focused on innovating the stent design to overcome migration and urinary reflux, as well as investigating novel materials and coatings to prevent biofilm formation, such as poly(N,Ndimethylacrylamide) (PDMMA) and swellable polyethylene glycol diacrylate (PEGDA). Biodegradable ureteral stents (BUS) have also emerged as a new generation of endourological devices, overcoming the “forgotten stent syndrome” and reducing healthcare costs. Moreover, efforts have been made to develop pre-clinical test methods, both experimental and computational, which could be employed as a screening platform to inform the design of novel stent technologies.

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More information

Accepted/In Press date: 28 June 2019
e-pub ahead of print date: 16 September 2019

Identifiers

Local EPrints ID: 433882
URI: http://eprints.soton.ac.uk/id/eprint/433882
ISSN: 2223-4691
PURE UUID: 50e2001c-f7b4-4c41-9c6e-21eeab9cbac9

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Date deposited: 05 Sep 2019 16:30
Last modified: 26 Nov 2021 06:30

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Contributors

Author: Bhaskar Somani
Author: Federico Soria
Author: Dario Carugo
Author: Ali Mosayyebi

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