Diabetes is associated with increased risk of hepatocellular carcinoma in non-alcoholic steatohepatitis with cirrhosis – implications for surveillance and future pharmacotherapy

Johnston, Michael P., Patel, Janisha and Byrne, Christopher (2020) Diabetes is associated with increased risk of hepatocellular carcinoma in non-alcoholic steatohepatitis with cirrhosis – implications for surveillance and future pharmacotherapy. Hepatobiliary Surgery and Nutrition, 9 (2), 230-234. (doi:10.21037/hbsn.2019.10.09).

Record type: Editorial

Abstract

Hepatocellular carcinoma (HCC) is the most common liver-related complication seen in patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (1). NASH is strongly associated with type 2 diabetes mellitus (T2DM) but it has also been apparent for a number of years that T2DM is associated with an increased risk of HCC independent of the presence of NASH (2).

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